dorsal/arxiv
View SchemaElectrophoresis of a polyelectrolyte through a nanopore
| Authors | Sandip Ghosal |
|---|---|
| Categories | |
| ArXiv ID | physics/0609244 |
| URL | https://arxiv.org/abs/physics/0609244 |
| DOI | 10.1103/PhysRevE.74.041901 |
| Journal | Phys. Rev. E 74, 041901 (2006) (5 pages) |
Abstract
A hydrodynamic model for determining the electrophoretic speed of a polyelectrolyte through a nanopore is presented. It is assumed that the speed is determined by a balance of electrical and viscous forces arising from within the pore and that classical continuum electrostatics and hydrodynamics may be considered applicable. An explicit formula for the translocation speed as a function of the pore geometry and other physical parameters is obtained and is shown to be consistent with experimental measurements on DNA translocation through nanopores in silicon membranes. Experiments also show a weak dependence of the translocation speed on polymer length that is not accounted for by the present model. It is hypothesized that this is due to secondary effects that are neglected here.
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"abstract": "A hydrodynamic model for determining the electrophoretic speed of a\npolyelectrolyte through a nanopore is presented. It is assumed that the speed\nis determined by a balance of electrical and viscous forces arising from within\nthe pore and that classical continuum electrostatics and hydrodynamics may be\nconsidered applicable. An explicit formula for the translocation speed as a\nfunction of the pore geometry and other physical parameters is obtained and is\nshown to be consistent with experimental measurements on DNA translocation\nthrough nanopores in silicon membranes. Experiments also show a weak dependence\nof the translocation speed on polymer length that is not accounted for by the\npresent model. It is hypothesized that this is due to secondary effects that\nare neglected here.",
"arxiv_id": "physics/0609244",
"authors": [
"Sandip Ghosal"
],
"categories": [
"physics.chem-ph",
"physics.bio-ph",
"physics.flu-dyn"
],
"doi": "10.1103/PhysRevE.74.041901",
"journal_ref": "Phys. Rev. E 74, 041901 (2006) (5 pages)",
"title": "Electrophoresis of a polyelectrolyte through a nanopore",
"url": "https://arxiv.org/abs/physics/0609244"
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