dorsal/arxiv
View SchemaAtomic Force Microscopy of height fluctuations of fibroblast cells
| Authors | Bálint Szabó, Dávid Selmeczi, Zsuzsanna Környei, Emília Madarász, Noémi Rozlosnik |
|---|---|
| Categories | |
| ArXiv ID | physics/0209007 |
| URL | https://arxiv.org/abs/physics/0209007 |
| DOI | 10.1103/PhysRevE.65.041910 |
| Journal | Phys.Rev. E65 (2002) 041910 |
Abstract
We investigated the nanometer scale height fluctuations of 3T3 fibroblast cells with the atomic force microscope (AFM) under physiological conditions. Correlation between these fluctuations and lateral cellular motility can be observed. Fluctuations measured on leading edges appear to be predominantly related to actin polymerization-depolymerization processes. We found fast (5 Hz) pulsatory behavior with 1--2 nm amplitude on a cell with low motility showing emphasized structure of stress fibres. Myosin driven contractions of stress fibres are thought to induce this pulsation.
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"abstract": "We investigated the nanometer scale height fluctuations of 3T3 fibroblast\ncells with the atomic force microscope (AFM) under physiological conditions.\nCorrelation between these fluctuations and lateral cellular motility can be\nobserved. Fluctuations measured on leading edges appear to be predominantly\nrelated to actin polymerization-depolymerization processes. We found fast (5\nHz) pulsatory behavior with 1--2 nm amplitude on a cell with low motility\nshowing emphasized structure of stress fibres. Myosin driven contractions of\nstress fibres are thought to induce this pulsation.",
"arxiv_id": "physics/0209007",
"authors": [
"B\u00e1lint Szab\u00f3",
"D\u00e1vid Selmeczi",
"Zsuzsanna K\u00f6rnyei",
"Em\u00edlia Madar\u00e1sz",
"No\u00e9mi Rozlosnik"
],
"categories": [
"physics.bio-ph",
"astro-ph",
"q-bio"
],
"doi": "10.1103/PhysRevE.65.041910",
"journal_ref": "Phys.Rev. E65 (2002) 041910",
"title": "Atomic Force Microscopy of height fluctuations of fibroblast cells",
"url": "https://arxiv.org/abs/physics/0209007"
},
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