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As at 30 September 2026

GLOBAL SUSTAINABLE EQUITY FUND

I Acc ISIN GB00B71DPP64

Marketing communication Page 1 / 4

Fund details

Inception date 01 August 1991 Total net assets 1.50bn Asset class Equities Domicile United Kingdom Structure OEIC Base currency GBP Index MSCI World Index SM Peer group IA Global sector SDR Label

Sustainable Disclosure Requirements Label: Sustainability Focus funds invests mainly in assets that focus on sustainability for people or the planet. For benchmark/usage description, refer to Additional fund information on page 3 . Share class information

Inception date 19 July 2012 Distribution type Accumulation Net Distribution frequency Biannually Historic yield 0.20% Currency GBP Minimum initial investment 3,000,000

The Historic Yield does not include any preliminary charge and investors may be subject to tax on their distributions. Portfolio management

Hamish Chamberlayne, CFA

Manager since 2013

Aaron Scully, CFA Manager since 2019

Ratings

Overall Morningstar Rating TM     As of 30/09/2026 Morningstar Medalist Rating TM Effective 27/04/2026 Analyst - Driven%: 100.00 Data Coverage%: 100.00 n/a For more information, refer to page 3 .

Investment objective The Fund aims to provide capital growth over the long term (5 years or more) by investing in companies that the Investment Manager believes contribute to positive environmental or social change by reference to the sustainability themes. The Investment Manager has identified nine environmental and social sustainability themes that it believes will help drive a sustainable global economy by addressing current global c hallenges such as population growth, ageing population, resource constraints and climate change. The Investment Manager will invest in companies whose products and/or services are aligned with the sustainability themes. For the fund’s investment policy, refer to the Additional fund information on page 3 . Past performance does not predict future returns.

Performance (%)

Returns

Cumulative Annualised

1 Month

3 Month YTD

1 Year

3 Year

5 Year

10 Year

Since inception (31/07/91) I Acc (Net) - 1.76 1.86 12.92 11.19 14.87 7.64 12.70 9.14 Index 0.88 1.86 13.49 17.23 18.51 12.73 13.11 9.80 Peer Group - 0.62 0.38 10.36 13.28 13.82 7.61 9.92 7.97

Cumulative growth – GBP

30 Sep 2021 — 30 Sep 2026

━━

Global Sustainable Equity Fund I Acc (Net) ━━ MSCI World TR ━━ IA Global

12 month rolling Sep 2025 Sep 2026

Sep 2024 Sep 2025

Sep 2023 Sep 2024

Sep 2022 Sep 2023

Sep 2021 Sep 2022 I Acc (Net) 11.19 11.53 22.23 6.76 - 10.72 Index 17.23 17.32 21.05 12.11 - 2.46 Peer Group 13.28 11.82 16.42 7.72 - 9.15 Performance is on a net of fees basis, with gross income reinvested. Source: at 30/09/26. © 2026 Morningstar, Inc. All rights reserved. The information contained herein: (1) is proprietary to Morningstar and/or its content providers; (2) may not be copied or distributed; and (3) is not warranted to be accurate, complete, or timely. Neither Morningstar nor its content providers are responsible for any damages or losses arising from any use of this information. Past performance does not predict future returns . Performance/performance target related data will display only where relevant to the share class inception date and annualised target time period. The value of an investment and the income from it can fall as well as rise and you may not get back the amou nt originally invested. Source for target returns (where applicable) - Janus Henderson Investors. The I Acc share class was launched on 19 July 2012. Performance prior to that date is past performance based on the I Inc share class of the same fund, which has a different fee structure.

-20

100

Sep-21 Sep-22 Sep-23 Sep-24 Sep-25 Sep-26

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Global Sustainable Equity Fund I Acc (as at 30/09/26)

Page 2 / 4

Top countries (%)

Regions (%)

Codes ISIN GB00B71DPP64 Bloomberg HENGCGI SEDOL B71DPP6 WKN A3DBYK Valoren 18754032 n/a n/a Fees & charges (%) Annual management charge (AMC) 0.75 Ongoing charge (OCF) 0.85 All ongoing charges stated are as per latest published report and accounts. Fund charges will impact the value of your investment. In particular, the ongoing charges applicable to each fund will dilute investment performance, particularly over time. For further explanation of charges please visit our Fund Charges page at www.janushenderson.com. Under some circumstances initial charges may apply. Please refer to the Prospectus for more d etails.

United States Japan Sweden Taiwan France Spain Austria Canada Hong Kong China

Fund 60.60 7.54 5.71 3.93 3.87 2.83 2.13 2.12 1.67 1.52

Index 72.94 5.91 0.80

— 2.24 0.95 0.09 3.29 0.43

—

North America Europe Japan Emerging Markets Pacific Region United Kingdom

Fund 62.73 18.19 7.54 5.45 1.67 1.31

Index 76.23 11.72 5.91 0.28 2.45 3.41

Characteristics Number of holdings: Equity issues 56 Active share 83.85% Weighted average market cap 589.00bn Price - to - book ratio 5.00 Price - to - earnings ratio 18.22 n/a n/a Risk statistics (3 years) Fund Index Beta 1.06 — Standard deviation 12.89 10.82 Sharpe ratio 0.76 1.23 Tracking error 5.89 —

Top holdings (%) Fund NVIDIA 6.83 Microsoft 5.99 Taiwan Semiconductor Manufacturing 3.93 McKesson 3.69 Spotify Technology 3.41 Arthur J Gallagher 2.92 Banco Bilbao Vizcaya Argentaria 2.83 Seagate Technology 2.64 Schneider Electric 2.60 Uber Technologies 2.54 Total 37.37 References made to individual securities do not constitute a recommendation to buy, sell or hold any security, investment strategy or market sector, and should not be assumed to be profitable. Janus Henderson Investors, its affiliated advisor, or its employees, may have a position in the securities mentioned.

Top sectors (%)

Market capitalisation of equity holdings (%) Fund Index Over £100B 38.50 62.56 £50B to £100B 22.99 15.22 £25B to £50B 20.93 11.39 £10B to £25B 9.43 9.15 £5B to £10B 4.96 1.63 Under £5B 0.07 0.04

Information Technology Industrials Financials Health Care Communication Services Consumer Discretionary Real Estate Cash

Fund 34.84 25.89 19.92 5.97 4.07 3.70 2.48 3.12

Index 31.78 10.80 15.74 9.20 8.31 8.36 1.52

—

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Global Sustainable Equity Fund I Acc (as at 30/09/26)

Page 3 / 4

Ratings & Awards

For the source and information on ratings and awards shown above, refer to Source for fund ratings/awards. Additional fund information

Tax assumptions and reliefs depend upon an investor’s particular circumstances and may be subject to change. From 15 December 2017, the Henderson Global Care Growth Fund changed its name and investment policy to become the Janus Henderson Global Sustainable Equ ity Fund. F rom 15 April 2025, the Fund's investment objective, policy and strategy changed. Fund size at 12pm on last business day of month. Please note: due to rounding the figures in the holdings breakdowns may not add up to 100%. Performance for the share class is calculated at 12pm and performance of the index is calculated as at close of business. Note that any differences among portfolio securities currencies, share class cur rencies and costs to be paid or represented in currencies other than your home currency will expose you to currency risk. Costs and returns may increase or decrease as a result of currency and exchange rate fluctuations. Country and sector breakdowns relate to end of day trading positions. Investment int o the fund will acquire units/shares of the fund itself and not the underlying assets owned by the fund. Cash balances and exposures are based on settled and unsettl ed trades as at the reporting date. The MSCI World Index is a measure of the combined performance of large and medium sized com panies from developed stock markets around the world. It provides a useful comparison against which the Fund's performance can be assessed over time. The Investment Association (IA) groups funds with similar geographic and/or investment remit into secto rs. The Fund's ranking within the sector (as calculated by a number of data providers) can be a useful performance comparison against other funds with similar aims. Investment policy The Fund invests at least 70% of its assets in shares (also known as equities) of companies, of any size, in any industry and in any country, provided that such companies are not excluded by virtue of the applicable exclusions and meet the Fund’s sustainability standard. Whether a company provides sust ainable products and/or services, and therefore whether it is a sustainable company for this Fund, will be determined by a ro bust evidence - based standard, which requires the majority of each company’s current revenues (at least 50%) to be aligned to a sing le sustainability theme. The Fund may also invest up to 30% of its assets in other assets including: (a) companies that have less than 50% revenues aligned to the sustainability themes or have revenues which the Investment Manager considers as enhancing qu ality of life and which are not considered to conflict with the sustainability themes: (b) companies that derive at least 50% of prospective revenues from products and services that contribute to positive environment al or social change; (c) Collective Inve stment Schemes (including those managed by Janus Henderson); and (d) cash. The Investment Manager may use derivatives (comple x financial instruments) to reduce risk or to manage the Fund more efficiently. The Fund is actively managed with reference to the MSCI World Index. The index represents the most appropriate and useful comparator for assessing the Fund's performance because there is a high degr ee of overlap between the constituents of the index and the initial investible universe of the Fund, but the index does not define the Fund’s investment universe. The Investment Manager has discretion to choose investments for the Fund that are not in the index or with weightings that are different com pared to the index. As an additional means of assessing the pe rformance of the Fund, the IA Global sector average, which is based on a peer group of broadly similar funds, may also provide a useful comparator. Investment strategy The Fund pursues its objectives by investing in sustainable companies that the Investment Manager believes contribute to positive environmental or social change and which have attractive financial prospects based on detailed analysis of financial statements and forecasted cash flows. The Fund has a bias towards “growth” equities. Th e “growth” approach emphasises investments in companies the Investment Manager believes have the potential for above - average earnings growth. Examples of themes the Investment Manager has identified include efficiency, cleaner energy, water m anagement, env ironmental services, sustainable transport, sustainable property & finance, safety, quality of life, knowledge & technology a nd health. More product specific information, including our investment principles, can be found in the Document Library of the webs ite at www.janushenderson.com. Further information as to how Janus Henderson approach ESG, including Janus Henderson’s “ESG Investment Policy”, can be found at www.janushenderson.com/esg - governance. Fund specific risks Shares can lose value rapidly, and typically involve higher risks than bonds or money market instruments. The value of your investment may fall as a result. Shares of small and mid - size companies can be more volatile than shares of larger companies, and at times it may be difficult to value or to sell shares at desired times and prices, increasing the risk of losses. The Fund follows a growth investment style that creates a bias towards certain types of companies. This may result in the Fund significantly underperforming or outperformin g the wider market. Due to the Fund’s Sustainability Approach, it may exclude or invest less or more in certain companies and may therefore perform differently to funds that have a similar fi nancial objective, but that do not have a binding Sustainability Approach. Political, regulatory or investor sentiment about sustainability initiatives may change over time and impact the Fund’s performance. Derivatives may be used with the aim of reducing risk or managing the portfolio more efficiently. However , this i ntroduces other risks, in particular, that a derivative counterparty may not meet its contractual obligations. If the Fund holds assets in cu rrencies other than the base currency of the Fund, or you invest in a share/unit class of a different currency to t he Fund (unless hedged, i.e. seeks to mitigate exchange rate movements between the share/unit class currency and the base currency of the Fund), the value of your investment may be impac ted by changes in exchange rates. When the Fund, or a share/unit class , seeks to mitigate exchange rate movements of a currency relative to the base currency (hedge), the hedging strategy itself may positively or negatively impact the value of the Fund due to differences in short - term interest rates between the currencies. S ecurities could become hard to value or to sell at a desired time and price, especially in extreme market conditions when ass et prices may be falling, increasing the risk of investment losses. Losses could be incurred if a counterparty became unwilling or unable to meet its obligations, or as a result of failure or delay in operational processes or the failure of a third party provider. Source for fund ratings/awards Overall Morningstar Rating™ is a measure of a fund's risk - adjusted return, relative to similar funds. Fund share classes are rated from 1 to 5 stars, with the best performers receiving 5 stars and the worst performers receiving a single star. Where available, overall Morningstar Rating™ is shown for share classes achievin g a rating of 4 or 5 stars. Morningstar Medalist Rating™ Ratings should not be taken as a recommendation. For more detailed information about Morningstar Ratings, including its methodology, please go to https://shareholders.morningstar.com/investor relations/governance/Compliance -- Disclosure/default.aspx . Funds worthy of Titan Square Mile recommendation's may be rated as AAA, AA or A. Ti tan Square Mile expects any active fund to add value over a corresponding passive strategy where such an option exists and this s hould be reflected in the fund’s objective. This added value is provided by the production of relatively high risk adjusted ret urns over a suitable time period. When rating funds Titan Square Miles constantly ask themselves whether they would be happy to invest our own money in the funds. The Titan Squa re Mile A rating is assigned to funds in which they have confidence that the fu nd over an investment cycle will meet its stated objectives. This fund has been rated by Titan Square Mile as at 01/07/2026. https://www.titansquaremile.com/research/ratings Ranges that ha ve successfully gone through the RSMR's rigorous and robust methodology will be awarded their Rated Fund Range designation. In giving this rating, RSMR are confirming that their research shows Janus Henderson Investors to have a sound investment process fo r the fund range, and that their analysis of the performance and risk of the range of funds is in line with their expectations. One of the primary reasons for separating out ranges from the sector funds that form RSMR’s usual reviews is to provide a

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Global Sustainable Equity Fund I Acc (as at 30/09/26)

Page 4 / 4

simple r process for advisers and provide analysis and guidance from a more practical perspective. By assessing the core processes a gainst objectives and targets rather than emphasising the peer group, RSMR feel they can identify those fund ranges in a way that a dvisers can then utilise across a range of clients or risk profiles more effectively and consistently. All the fund ranges that have been awarded a rating will be li sted on the RSMR website, where you will also find a factsheet for each range. All this inf ormation should enable you to understand the fund ranges that are available, and the key differences between them, meaning you can then determine which, if any, is most suitable for you. This fund has been rated by RSMR as at 01/01/2026. https://www.rsmr.c o.uk.

Glossary

Active share This measures how much a portfolio's holdings differ from its benchmark index. For example, a portfolio with an active share of 60% indicates that 60% of its holdings differ from its benchmark, while the remaining 40% mirror the benchmark. Beta Beta measures how a fund or security moves in relationship to the overall market. A market has a beta of 1. If the fund/secur ity’s beta is more than 1, it moves more than the market, while a beta lower than 1 means it moves to a lesser extent than the market. A negative beta could mean the fund/security moves in the opposite direction to the market. Historic Yield The Historic Yield reflects distributions declared over the past 12 months as a percentage of the mid - market share p rice, as at the date shown. Price - to - book (P/B) ratio A financial ratio used to value a company's shares. It is calculated by dividing a company’s market value (share price) by th e book value of its equity (value of the company's assets on its balance sheet). A P/B value <1 can indicate a potentially undervalued company or a declining business. The higher the P/B ratio, the higher the premium the market is willing to pay for the company above the book (balance sheet) value of it s assets. Price - to - earni ngs (P/E) ratio A popular ratio used to value a company’s shares, compared to other stocks, or a benchmark index. It is calculated by dividin g the current share price by its earnings per share. Sharpe ratio This measures a portfolio's risk - adjusted perfor mance. A high Sharpe ratio indicates a better risk - adjusted return. The ratio is designed to measure how far a portfolio’s return can be attributed to fund manager skill as opposed to excessive risk taking. Standard deviation A statistic that measures the variation or dispersion of a set of values/data. A low standard deviation shows the values tend to be close to the mean while a high standard deviation indicates the values are more spread out. In terms of valuing investments, standard deviation can p rovi de a gauge of the historical volatility of an investment. Tracking error This measures how far a portfolio’s actual performance differs from its benchmark index. The lower the number, the more close ly it resembles the index. Weighted average market cap T he average market capitalisation of a holding, weighted by the size of that position in a portfolio or index.

FOR MORE INFORMATION PLEASE VISIT JANUSHENDERSON.COM

The Global Sustainable Equity fund avoids companies engaged in fossil fuel power generation, however, the fund may invest in companies generating power from natural gas where the company’s strategy involves a transition to renewable energy. Investment in such companies i s permitted where carbon intensity is aligned with a be low 2°C scenario. Where carbon intensity cannot be determined, a 10% threshold for energy production from natural gas is used. Unless otherwise indicated all figures sourced from Morningstar, Datastream, BNP Paribas and Janus Henderson Investors. Marke ting Communication. Past performance does not predict future returns. Please note the views, opinions and forecasts expressed in this document ar e based on Janus Henderson Investors research, analysis and house views at the time of publication. Third party data is believed to be reliable, but its completeness and accuracy is not guaranteed. Please read all scheme documents before investing. Before entering into an investment agreement i n respect of an investment referred to in this document, you should cons ult your own professional and/or investment adviser. The value of an investment and the income from it can fall as well as rise and you may not get back the amount originally invested. Tax assumptions and reliefs depend upon an investor’s particular circum stances and may change if those circumstances or the law change. If you invest through a third party provider you are advised to consult them directly as charges, performance and terms and conditions may differ materially than those shown on this document. Nothing in this document is intended to or should be construed as advice. This communication does not constitute an offer or a recommendation to sell or purchase any investment. It does not form part of any contract for the sale or purchase of any investm ent. Any investment application will be made solely on the basis of the information contained in the Prospectus (including all relevant covering documents), which will contain investment restrictions. This doc ument is intended as a summary only and potenti al investors must read the prospectus, and where relevant, the key investor information document before investing. We may record telephone calls for our mutual protection, to improve customer service and for regulatory record keeping purposes. Iss ued in UK by Janus Henderson Investors. Janus Henderson Investors is the name under which investment products and services are provided by Janus Henderson Investors International Limited (reg no. 3594615), Janus Henderson Investors UK Limited (reg. no. 906355), Jan us Henderson Fund Management UK Limited (reg. no. 2678531), Tabula Investment Management Limited (reg. no. 11286661), (each registered in England and Wales at 201 Bishopsg ate, London EC2M 3AE and regulated by the Financial Conduct Authority) and Janus Hend erson Investors Europe S.A. (reg no. B22848 at 78, Avenue de la Liberté, L - 1930 Luxembourg, Luxembourg and regulated by the Commission de Surveillance du Secteur Financier). In Ireland the Facilities Agent is BNP Paribas Fund Administration Services (Irela nd) Limited. Janus Henderson® and any other trademarks used herein are trademarks of Janus Henderson Group Ltd. or one of its subsidiaries. © Janus Henderson Group Ltd.

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