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* 1st NAV date: 16/04/2012 Source(s): BNPP Asset Management as at 30/09/2026 For more information about BNPP Asset Management, visit bnpparibas-am.com
AXA Framlington Biotech Fund Z GBP
Factsheet: 30/09/2026 EQUITY Marketing communication
Past performance is not a reliable indicator of future results.
Key Figures (GBP) *
Fund Cumulative Performance (%)
YTD 1Y 3Y 10Y Launch +3.17 +20.97 +35.04 +120.82 +548.93
Current NAV
Acc. Inc. 6.501 2.233
Fund Annualized Performance (%)
3 Y. 5 Y. 10 Y. Launch +10.51 +5.25 +8.24 +13.80
Assets Under Management (M)
GBP 344.07
Performance & Risk
Performance Evolution (GBP)
Portfolio* (35.04%) Benchmark (68.10%)
29/09/23 30/03/2 4 30/09/2 4 30/03/25 30/09/25 30/03/26 30/09/26
80
100
120
140
160
180
Data is rebased to 100 by BNPP AM on the graph start date Cumulative performance calculations are net of fees, based on the reinvestment of dividends. The benchmark, when there is one could be calculated on the basis of net or gross dividend. Please refer to the prospectus (or Swiss fund contract) for more information.
Risk Analysis
1Y 3Y 5Y Launch Portfolio Volatilit y* (%) 17.89 20.39 18.44 20.70 Benchmar k Volatilit y (%) 19.14 18.57 17.12 19.49
R elative R is k /Trac k ing Error (%) 15.73 8.20 8.30 8.35 S harpe R atio 0.99 0.32 0.11 0.62 Information R atio -1.69 -0.91 -0.18 0.04
All definitions of risks indicators are available in the section 'Glossary' below
Benchmark
Since: 01/06/2024 100% NA S DAQ Biotechnolog y Total R eturn Inde x The Fund is actively managed with deviation expected in term of constitution and performance compared to benchmark that is likely to be significant.
Fund Key Metrics
Port. Bench. Number of H oldings 53 245 Turnover: R olling 1Y (%) 12 Active S hare (%) 50 -
Fund Manager
Catherine TENNY SO N
Christopher ECCLE S - Co-Manager
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* 1st NAV date: 16/04/2012 Source(s): BNPP Asset Management as at 30/09/2026 For more information about BNPP Asset Management, visit bnpparibas-am.com
Performance & Risk (Continued)
Rolling Performance (%)
1M 3M 6M YTD 3Y 5Y 30/09/25 30/09/26
30/09/2 4 30/09/25
30/09/23 30/09/2 4
30/09/22 30/09/23
30/09/21 30/09/22 Launch
Portfolio * -7.05 -3.47 6.92 3.17 35.04 29.19 20.97 -0.09 11.74 -6.58 2.40 548.93 Benchmar k 2.16 8.40 21.30 26.77 68.10 44.37 48.58 2.82 10.04 -4.03 -10.51 604.70 E x cess R eturn -9.21 -11.88 -14.37 -23.59 -33.06 -15.18 -27.61 -2.91 1.70 -2.55 12.91 -55.78
Annual Calendar Performance (%)
2025 202 4 2023 2022 2021 2020 2019 201 8 201 7 2016 Portfolio * 21.17 0.95 1.82 3.77 3.39 32.74 19.35 -6.42 9.66 -4.95 Benchmar k 24.24 0.84 -2.11 0.32 0.28 21.80 19.61 -3.69 10.58 -6.59 E x cess R eturn -3.07 0.11 3.93 3.45 3.11 10.94 -0.26 -2.73 -0.92 1.64
Past performance is not a reliable indicator of future results. Performance calculations are net of fees, based on the reinvestment of dividends. The benchmark, when there is one could be calculated on the basis of net or gross dividend. Please refer to the prospectus for more information.
Portfolio Analysis
Top 10 Holdings
E q uit y W eighting (%) S ector Geograph y Portfolio Benchmar k R elative Vertex Pharmaceuticals Inc 8.42 7.69 0.73 Biotechnology N orth A merica A mgen Inc 7.74 7.85 -0.11 Biotechnology N orth A merica R egeneron Pharmaceuticals Inc 7.19 5.03 2.16 Biotechnology N orth A merica Gilead Sciences Inc 7.04 8.16 -1.11 Biotechnology N orth A merica A rgenx S E 5.06 1.71 3.34 Biotechnology E urope E x UK RE V OLU TI ON Medicines Inc 4.32 2.88 1.43 Biotechnology N orth A merica Insmed Inc 3.84 1.63 2.21 Biotechnology N orth A merica U nited Therapeutics Corp 3.37 1.52 1.85 Biotechnology N orth A merica Beigene L td 2.58 0.86 1.72 Biotechnology E merging A lnylam Pharmaceuticals Inc 2.56 2.16 0.40 Biotechnology N orth A merica Total (%) 52.12 39.51 Any securities or other financial instruments shown are for illustrative purposes only at the date of this report and and may no longer be in the portfolio later. This should not be considered as a recommendation to purchase or sell any security or other financial instrument.
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Source(s): BNPP Asset Management as at 30/09/2026 For more information about BNPP Asset Management, visit bnpparibas-am.com
Portfolio Analysis (Continued) Top 5 Overweight (%)
Port. Bench. R elative A rgenx S E 5.06 1.71 3.34 Insmed Inc 3.84 1.63 2.21 R egeneron Pharmaceuticals Inc 7.19 5.03 2.16 A straZeneca P L C 2.15 0.00 2.15 Mirum Pharmaceuticals Inc 2.44 0.36 2.08
Top 5 Underweight (%)
Port. Bench. R elative Moderna Inc 0.00 5.04 -5.04 Illumina Inc 0.00 2.71 -2.71 Biogen Inc 0.00 2.19 -2.19 R oivant Sciences L td 0.00 1.73 -1.73 R oyalty Pharma Plc- Cl A 0.00 1.70 -1.70
S ector Breakdown (%)
Portfolio Benchmar k Biotechnology 94.80 81.06 Pharmaceuticals 3.84 10.56 L ife Sciences Tools & Services 0.00 6.60 H ealth Care Services 0.00 1.64 H ealth Care Eq uipment 0.00 0.15 Cash 1.36 0.00
Active E x posure b y S ector (%)
- 8 -6 - 4 -2 0 2 4 6 8 10 12 1 4
G eographical Breakdown (%)
Portfolio Benchmar k N orth A merica 81.01 94.70 E urope E x UK 9.86 3.87 UK 4.09 0.27 E merging 2.58 1.10 D eveloped A sia Pacific ex J apan 1.10 0.05 Cash 1.36 0.00
Active E x posure b y G eography (%)
-1 4 -12 -10 - 8 -6 - 4 -2 0 2 4 6
MarketCap Breakdown (GBP - %)
0 To 250mn
250mn To 500mn
500mn To 1bn 1bn To 3bn 3bn To 5bn 5bn To 10bn 10bn To 25bn 25bn To 100bn 100bn To 250bn Cash 0
10
20
30
40
Port. 0.41 1.53 1.30 15.48 6.65 11.87 16.89 27.56 16.93 1.36 Bench. 0.52 1.03 2.05 10.44 6.70 14.50 29.99 18.76 16.01 -
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Source(s): BNPP Asset Management as at 30/09/2026 For more information about BNPP Asset Management, visit bnpparibas-am.com
Additional I nformation
Administration : Z G BP
Legal form U nit Trust UCIT S Compliant Y es AIF Compliant N o Legal countr y U nited K ingdom 1st NAV date 16/04/2012 Fund currenc y GBP S hareclass currenc y GBP Valuation D aily S hare t y pe A ccumulation / Income I S IN code C / D GB00B784 N S11 / GB00B RJ ZV L 27 Bloomberg Code C / D F RA BI O Z LN / F RA BIZI LN S ED O L Code C / D B784 N S1 / B RJ ZV L 2 ME X Code C / D F R B O T H / ELA B HN Transaction costs 0.40% O ngoing charges 0.82% Financial management fees 0.75% Ma x imum management fees 0.75% Minimum initial subscription 100 000 GBP Minimum subse q uent subcription 5 000 GBP
Management compan y AXA I N V E STM EN T M ANA G ER S UK L IMIT ED Delegation of account administration
ST A T E ST REE T B ANK AND T RU ST C O MP ANY Custodian H SBC B ANK P L C
The actual costs can be found in the annual reports and are deducted each time the net asset value is calculated. The value of the investment is reduced by these costs. As disclosed in the most recent Annual Report, the ongoing charges calculation excludes performance fees, but includes management and applied services fees. The effective Applied Service Fee is accrued at each calculation of the Net Asset Value and included in the ongoing charges of each Share Class. The investment will be reduced by the payment of the above mentioned fees. Fund O bj ectives
The aim of this Fund is to provide long-term capital growth over a period of 5 years or more.
I nvestment Hori z on
This Fund may not be suitable for investors who plan to withdraw their contribution within five years.
Risk I ndicator
The information shown below is from the U CITS K II D .
Lo w er ris k H igher ris k
Potentially lower reward Potentially higher reward
1 2 3 4 5 6 7
The risk category is calculated using historical performance data and may not be a reliable indicator of the Fund ' s future risk profile.
The risk category shown is not guaranteed and may shift over time The lowest category does not mean risk free. W hy is this S u b- Fund in this category ? The capital of the Fund is not guaranteed. The Fund is invested in financial markets and uses techni q ues and instruments which may be sub j ect to sudden and significant variation , which may result in substantial gains or losses.
Additional Risk Counterpart y R is k : failure by any counterparty to a transaction (e.g. derivatives and securities lending) with the Fund to meet its obligations may adversely affect the value of the Fund. The Fund may receive assets from the counterparty to protect against any such adverse effect but there is a risk that the value of such assets at the time of the failure would be insufficient to cover the loss to the Fund.
S ingle S ector R is k : as this Fund is invested in a single sector , the Fund ' s value will be more closely aligned with the performance of that sector and it may be sub j ect to greater fluctuations in value than more diversified funds.
Currenc y R is k : the Fund holds investments denominated in currencies other than the base currency of the Fund. A s a result , exchange rate movements may cause the value of investments (and any income received from them) to fall or rise affecting the Fund ' s value.
Further explanation of the risks associated with an investment in this Fund can be found in the prospectus.
S u b scription Redemption
Y our orders to buy , sell or transfer units in the Fund must be received by the A dministrator by 12 noon on any working day , to receive that days Fund price. Please note that if your order is placed by an intermediary or Financial A dviser they may re q uire extra processing time.The N et A sset Value of this Fund is calculated on a daily basis.
Minimum initial investment: £ 100 , 000 Minimum subse q uent investment: £ 5 , 000
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Source(s): BNPP Asset Management as at 30/09/2026 For more information about BNPP Asset Management, visit bnpparibas-am.com
Additional I nformation (Continued)
How to I nvest
Before ma k ing an investment, investors should read the relevant Prospectus and the K e y Investor Information Document (particularl y for U K investors) / K e y Information Document / scheme documents, w hich provide full product details including investment charges and ris k s. These documents are available in English or in y our national language (if available) at a x a-im.com. The information contained herein is not a substitute for those documents or for professional external advice. R etail Investors R etail investors should contact their Financial intermediary.
D isclaimers
Not for distribution or dissemination to U S investors
This marketing communication does not constitute on the part of B N PP A sset Management a solicitation or investment , legal or tax advice. This material does not contain sufficient information to support an investment decision. The information contained herein is intended solely for the entity and/or person(s) to which it has been delivered , unless otherwise allowed under applicable agreements.
The tax treatment associated with holding , buying or disposing of shares or units in a fund depends on the status or tax treatment of each investor and may be sub j ect to change. Potential investors are strongly encouraged to seek the advice of their own tax adviser.
D ue to its simplification , this document is partial and opinions , estimates and forecasts herein are sub j ective and sub j ect to change without notice. There is no guarantee forecasts made will come to pass. D ata , figures , declarations , analysis , predictions and other information in this document is provided based on our state of knowledge at the time of creation of this document. W hilst every care is taken , no representation or warranty (including liability towards third parties) , express or implied , is made as to the accuracy , reliability or completeness of the information contained herein. This material does not contain sufficient information to support an investment decision.
Past performance is not a guide to current or future performance , and any performance or return data displayed does not take into account commissions and costs incurred when issuing or redeeming units. The value of investments , and the income from them , can fall as well as rise and investors may not get back the amount originally invested. E xchange-rate fluctuations may also affect the value of their investment. D ue to this and the initial charge that is usually made , an investment is not usually suitable as a short term holding. Commissions and costs have an adverse effect on the performance of the fund.
The Fund ’ s characteristics do not protect the investors from the potential effect of inflation over time. The investments and/or any potential income generated during the period will not be ad j usted by the rate of inflation over the same period. Thus , the return on the fund ad j usted from the rate of inflation could be negative. Conse q uently , the inflation might undermine the performance and/or the value of your investment.
The Fund referenced herein has not been registered under the U nited States Investment Company A ct of 1940 , as amended , nor the U nited States Securities A ct of 1933 , as amended. N one of the shares may be offered or sold , directly or indirectly in the U nited States or to any U S Person unless the securities are registered under the A ct , or an exemption from the registration re q uirements of the A ct is available. A U S Person is defined as (a) any individual who is a citi z en or resident of the U nited States for federal income tax purposes ; (b) a corporation , partnership or other entity created or organi z ed under the laws of or existing in the U nited States ; (c) an estate or trust the income of which is sub j ect to U nited States federal income tax regardless of whether such income is effectively connected with a U nited States trade or business. In the U nited States , this material may be distributed only to a person who is a “ distributor ,” or who is not a “U .S. person ,” as defined by R egulation S under the U .S. Securities A ct of 1933 (as amended).
If this is a part of AXA Framlington R ange of A uthorised U nit Trust Schemes , it is managed by AXA Investment Managers UK L imited. AXA Investment Managers UK L imited , is authorised and regulated by the Financial Conduct A uthority in the UK . R egistered in E ngland and W ales N o: 01431068. R egistered O ffice: 22 Bishopsgate , L ondon E C2 N 4B Q . In other j urisdictions , this document is issued by B N PP A sset Management ’ s affiliates in those countries.
For the purposes of presenting the breakdown by country , sector , principal exposures and active strategies , e q uities and similar instruments relating to a single company ( ADR s , G DR s , R SPs , rights , etc.) are grouped in order to form a single exposure for the said company.
The geographical breakdown is based on the country classification as published by the index provider (or the main index provider in case of a composite benchmark). The second available source is the Country IS O from Bloomberg (or U ltimate Country of risk for E merging fund).
A nnual turnover rate : Sum the last 12 monthly results to obtain the turnover rate over 1 rolling year , calculated according to the following formula: (abs(purchase) + abs(sale) - abs(subscription - redemption) ) / (2* average AU M). Purchase and sale exclude derivatives , short term instruments and some corporate actions. Subscription and redemption are netted on a monthly basis , impact of inflows and outflows can result in negative turnover which does not reflect portfolio turnover , therefore annual turnover has a floor of 0.
Securities or other financial instruments shown are for illustrative purposes only at the date of this report and may no longer be in the portfolio later. This does not constitute investment research or financial analysis relating to transactions in financial instruments , nor does it constitute an offer to buy or sell any investments , products or services , and should not be considered as solicitation or investment , legal or tax advice , a recommendation for an investment strategy or a personali z ed recommendation to buy or sell securities or other financial instruments.
For more information on sustainability-related aspects please visit https://www.axa-im.com/what-sfdr
Depending on the recipient ’ s respective j urisdiction or region, the follo w ing additional disclosures ma y appl y :
For Chilean Investors: This private offer avails itself of the General R egulation N o. 336 of the Superintendence of Securities and
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Source(s): BNPP Asset Management as at 30/09/2026 For more information about BNPP Asset Management, visit bnpparibas-am.com
Additional I nformation (Continued)
Insurances (currently the Financial Markets Commission). This offer relates to securities not registered with the Securities R egistry or the R egistry of Foreign Securities of the Financial Markets Commission , and therefore such securities are not sub j ect to oversight by the latter ; Being unregistered securities , there is no obligation on the issuer to provide public information in Chile regarding such securities ; and these securities may not be sub j ect to a public offer until they are registered in the corresponding Securities R egistry. Para inversionistas chilenos: E ST A O F ER T A P R IV ADA S E A C O G E AL RE G LA M EN T O G ENERAL Nº 336 DE LA S U P ER I N T ENDEN CI A DE V ALORE S Y S E G URO S ( A CT UAL M EN T E C O MISI ÓN DE M ER C ADO S FI NAN CI ERO S). E ST A O F ER T A S E RE FI ERE A V ALORE S NO I N SC R IT O S EN EL RE GIST RO DE V ALORE S O EN EL RE GIST RO DE V ALORE S EX T RANJERO S QUE LLE V A LA C O MISI ÓN DE M ER C ADO S FI NAN CI ERO S , P OR LO QUE T ALE S V ALORE S NO E ST ÁN S UJE T O S A LA FISC AL IZ A CI ÓN DE É ST A; P OR T RA T AR S E DE V ALORE S NO I N SC R IT O S NO EX IST E LA O B L IG A CI ÓN P OR P AR T E DEL E MIS OR DE EN T RE G AR EN C H I LE I N F OR M A CI ÓN P Ú B L IC A RE SP E CT O A LO S V ALORE S S O B RE LO S QUE S E RE FI ERE E ST A O F ER T A; E ST O S V ALORE S NO P ODRÁN S ER O B JE T O DE O F ER T A P Ú B L IC A MI EN T RA S NO S EAN I N SC R IT O S EN EL RE GIST RO DE V ALORE S C ORRE SP OND I EN T E . For Peruvian Investors: B N PP A sset Management is not licensed and it is not legally re q uired to be licensed by the Peruvian Securities R egulator (Superintendencia del Mercado de Valores - SMV) for these activities. Conse q uently , the Peruvian Securities R egulator does not exercise any kind of supervision regarding this fund , strategy and/or service ; and , the information furnished to the investors and the rest of the services rendered by B N PP A sset Management are sub j ect to its exclusive responsibility. In Peru , this document is only for the exclusive use of persons or entities q ualifying as " Invesionistas Institucionales " under Peruvian L aw. This document is not for public distribution. B N PP A sset Management no tiene y no est á legalmente obligada a tener una autori z aci ó n por parte de la Superintendencia del Mercado de Valores para estas actividades. E n consecuencia , la Superintendencia del Mercado de Valores no e j erce ning ú n tipo de supervisi ó n sobre el fondo , la estrategia , y/o los servicios ; y la informaci ó n proporcionada a los inversionistas y los dem á s servicios q ue les presta son de exclusiva responsabilidad de B N PP A sset Management. E n el Per ú, este documento es para el uso exclusivo de personas o entidades q ue califi q uen como " Inversionistas Institucionales " ba j o las leyes peruanas. E ste documento no es para distribuci ó n al p ú blico. For Urugua y an Investors: The sale of the shares/units q ualifies as a private placement pursuant to section 2 of U ruguayan law 18 , 627. The shares/units must not be offered or sold to the public in U ruguay , except in circumstances which do not constitute a public offering or distribution under U ruguayan laws and regulations. The shares/units are not and will not be registered with the Financial Services Superintendency of the Central Bank of U ruguay. The shares/units correspond to investment funds that are not investment funds regulated by U ruguayan law 16 , 774 dated September 27 , 1996 , as amended. For S ingapore Investors: This document is issued by B N P P AR IB A S A SS E T M ANA G E M EN T Singapore L td. ( " B N PP A M Singapore " ) ( R egistration N o. 199308471 D ) for the use of Institutional Investors and/or A ccredited Investors only as defined in Section 4 A of the Securities and Futures A ct (Cap. 289) (sub j ect to the Fund being registered under the R estricted Schemes) , and must not be relied upon by retail investors. Circulation must be restricted accordingly. A s an exempt financial adviser under the Financial A dvisers A ct ( " F AA" ) ,
B N PP A M Singapore is exempted from complying with certain business conduct rules (including but not limited to Sections 25 , 27 and 36 of the F AA ) when providing financial advisory services to A ccredited Investors. For H ong K ong investors: The authorisation of any fund by the Securities and Futures Commission in H ong K ong ( " SFC " ) does not imply official approval or recommendation. SFC authori z ation of a fund is not a recommendation or endorsement of a fund nor does it guarantee the commercial merits of a fund or its performance. It does not mean the fund is suitable for all investors nor is it an endorsement of its suitability for any particular investor or class of investors. W here any of the Funds is not authori z ed by the SFC , the information contained herein in connection with such unauthori z ed Fund is solely for the use of professional investors in H ong K ong. Materials exempted from authori z ation by the SFC have not been reviewed by the SFC. For Tai w an investors: The offer , distribution , sale or re-sale of fund units/shares in Taiwan re q uires approval from and/or registration with Taiwanese regulatory authorities. To the extent that any units/shares of the Funds are not so licensed or registered , such units/shares are made available in Taiwan on a private placement basis only to banks , bills houses , trust enterprises , financial holding companies and other q ualified entities or institutions (collectively , "Q ualified Institutions " ) and other entities and individuals meeting specific criteria ( "O ther Q ualified Investors " ) pursuant to the private placement provisions of the R ules Governing O ffshore Funds. N o other offer or sale of such units/shares in Taiwan is permitted. Taiwanese purchasers of such units/shares may not sell or otherwise dispose of their holdings except by redemption , transfer to a Q ualified Institution or O ther Q ualified Investor , transfer by operation of law or other means approved by the Taiwan Financial Supervisory Commission. If this is a part of AXA Framlington R ange of A uthorised U nit Trust Schemes , it is managed by AXA Investment Managers UK L imited , part of the AXA IM Group. AXA Investment Managers UK L imited , is authorised and regulated by the Financial Conduct A uthority in the UK . R egistered in E ngland and W ales N o: 01431068. R egistered O ffice: 22 Bishopsgate , L ondon E C2 N 4B Q . In other j urisdictions , this document is issued by AXA Investment Managers S A’ s affiliates in those countries.
For investors located in the European Union : Please note that the management company reserves the right , at any time , to no longer market the product(s) mentioned in this communication in the E uropean U nion by filing a notification to its supervision authority , in accordance with E uropean passport rules. In the event of dissatisfaction with B N PP A sset Management products or services , you have the right to make a complaint , either with the marketer or directly with the management company (more information on B N PP A sset Management complaints policy is available in E nglish: https://www.bnpparibas-am.com/en/complaint-management-policy/ ) . If you reside in one of the E uropean U nion countries , you also have the right to take legal or extra- j udicial action at any time. The E uropean online dispute resolution platform allows you to submit a complaint form (available at: https://ec.europa.eu/consumers/odr/main/index.cfm ? event = main. home.choose L anguage) and provides you with information on available means of redress (available at: https://ec.europa.eu/consumers/odr/main/ ? event = main.adr.show2) . Summary of investor rights in E nglish is available on B N PP A sset Management website https://www.bnpparibas-am.com/en-gb. Translations into other languages are available on local B N PP A sset
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Page 7
Source(s): BNPP Asset Management as at 30/09/2026 For more information about BNPP Asset Management, visit bnpparibas-am.com
Additional I nformation (Continued)
Management entities ' websites.
G lossary
Volatility (%): is an indicative measure of degree of variation of an asset ’ s price changes over time.
R elative R isk/Tracking E rror (%): measures , in standard deviation , the fluctuation of returns of a portfolio relative to the fluctuation of returns of a reference index. The tracking error can be viewed as an indicator of how actively a fund is managed. The lower the number the closer the fund ’ s historic performance has followed its benchmark.
Sharpe ratio: is the measure of the risk-ad j usted excess return over risk free rate of a financial portfolio and is used to compare the excess return of an investment to its risk. The higher the Sharpe ratio the better the return compared to the risk taken.
Information R atio (I R ): is a measurement of portfolio returns above the returns of a benchmark to the volatility of those excess returns. The I R is used to compare excess return over a benchmark to excess risk over a benchmark. E .g : A manager who outperforms a benchmark by 2% p.a. will have a higher I R than a manager with the same outperformance who has taken more risk.
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