dorsal/arxiv
View SchemaEffects of bone- and air-tissue inhomogeneities on the dose distributions of the Leksell Gamma Knife$^{\circledR}$ calculated with PENELOPE
| Authors | Feras M. O. Al-Dweri, E. Leticia Rojas, Antonio M. Lallena |
|---|---|
| Categories | |
| ArXiv ID | physics/0510173 |
| URL | https://arxiv.org/abs/physics/0510173 |
| DOI | 10.1088/0031-9155/50/23/018 |
Abstract
Monte Carlo simulation with PENELOPE (v.~2003) is applied to calculate Leksell Gamma Knife$^{\circledR}$ dose distributions for heterogeneous phantoms. The usual spherical water phantom is modified with a spherical bone shell simulating the skull and an air-filled cube simulating the frontal or maxillary sinuses. Different simulations of the 201 source configuration of the Gamma Knife have been carried out with a simplified model of the geometry of the source channel of the Gamma Knife recently tested for both single source and multisource configurations. The dose distributions determined for heterogeneous phantoms including the bone- and/or air-tissue interfaces show non negligible differences with respect to those calculated for a homogeneous one, mainly when the Gamma Knife isocenter approaches the separation surfaces. Our findings confirm an important underdosage ($\sim$10%) nearby the air-tissue interface, in accordance with previous results obtained with PENELOPE code with a procedure different to ours. On the other hand, the presence of the spherical shell simulating the skull produces a few percent underdosage at the isocenter wherever it is situated.
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"abstract": "Monte Carlo simulation with PENELOPE (v.~2003) is applied to calculate\nLeksell Gamma Knife$^{\\circledR}$ dose distributions for heterogeneous\nphantoms. The usual spherical water phantom is modified with a spherical bone\nshell simulating the skull and an air-filled cube simulating the frontal or\nmaxillary sinuses. Different simulations of the 201 source configuration of the\nGamma Knife have been carried out with a simplified model of the geometry of\nthe source channel of the Gamma Knife recently tested for both single source\nand multisource configurations. The dose distributions determined for\nheterogeneous phantoms including the bone- and/or air-tissue interfaces show\nnon negligible differences with respect to those calculated for a homogeneous\none, mainly when the Gamma Knife isocenter approaches the separation surfaces.\nOur findings confirm an important underdosage ($\\sim$10%) nearby the air-tissue\ninterface, in accordance with previous results obtained with PENELOPE code with\na procedure different to ours. On the other hand, the presence of the spherical\nshell simulating the skull produces a few percent underdosage at the isocenter\nwherever it is situated.",
"arxiv_id": "physics/0510173",
"authors": [
"Feras M. O. Al-Dweri",
"E. Leticia Rojas",
"Antonio M. Lallena"
],
"categories": [
"physics.med-ph"
],
"doi": "10.1088/0031-9155/50/23/018",
"title": "Effects of bone- and air-tissue inhomogeneities on the dose distributions of the Leksell Gamma Knife$^{\\circledR}$ calculated with PENELOPE",
"url": "https://arxiv.org/abs/physics/0510173"
},
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