dorsal/arxiv
View SchemaDisorder in DNA-Linked Gold Nanoparticle Assemblies
| Authors | Nolan C. Harris, Ching-Hwa Kiang |
|---|---|
| Categories | |
| ArXiv ID | physics/0507014 |
| URL | https://arxiv.org/abs/physics/0507014 |
| DOI | 10.1103/PhysRevLett.95.046101 |
Abstract
We report experimental observations on the effect of disorder on the phase behavior of DNA-linked nanoparticle assemblies. Variation in DNA linker lengths results in different melting temperatures of the DNA-linked nanoparticle assemblies. We observed an unusual trend of a non-monotonic ``zigzag'' pattern in the melting temperature as a function of DNAlinker length. Linker DNA resulting in unequal DNA duplex lengths introduces disorder and lowers the melting temperature of the nanoparticle system. Comparison with free DNA thermodynamics shows that such an anomalous zigzag pattern does not exist for free DNA duplex melting, which suggests that the disorder introduced by unequal DNA duplex lengths results in this unusual collective behavior of DNA-linked nanoparticle assemblies.
{
"annotation_id": "f4eec60b-7c95-402b-84ae-1ea2dfc958bf",
"date_created": "2026-03-02T18:01:00.750000Z",
"date_modified": "2026-03-02T18:01:00.750000Z",
"file_hash": "0b40fc810ebf57bf0de7e487213bed93b52a124ef93ff268c4430e11a31537dc",
"private": false,
"record": {
"abstract": "We report experimental observations on the effect of disorder on the phase\nbehavior of DNA-linked nanoparticle assemblies. Variation in DNA linker lengths\nresults in different melting temperatures of the DNA-linked nanoparticle\nassemblies. We observed an unusual trend of a non-monotonic ``zigzag\u0027\u0027 pattern\nin the melting temperature as a function of DNAlinker length. Linker DNA\nresulting in unequal DNA duplex lengths introduces disorder and lowers the\nmelting temperature of the nanoparticle system. Comparison with free DNA\nthermodynamics shows that such an anomalous zigzag pattern does not exist for\nfree DNA duplex melting, which suggests that the disorder introduced by unequal\nDNA duplex lengths results in this unusual collective behavior of DNA-linked\nnanoparticle assemblies.",
"arxiv_id": "physics/0507014",
"authors": [
"Nolan C. Harris",
"Ching-Hwa Kiang"
],
"categories": [
"physics.bio-ph",
"physics.chem-ph"
],
"doi": "10.1103/PhysRevLett.95.046101",
"title": "Disorder in DNA-Linked Gold Nanoparticle Assemblies",
"url": "https://arxiv.org/abs/physics/0507014"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "d5db16be-29a6-42d7-8955-ea40598fbcc7",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}