dorsal/arxiv
View SchemaThe role of synaptic facilitation in coincidence spike detection
| Authors | Jorge F. Mejias, Joaquin J. Torres |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0605006 |
| URL | https://arxiv.org/abs/q-bio/0605006 |
Abstract
Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal coincidences of spikes arriving at certain frequency from N different afferents. We extend a previous work that only considers synaptic depression as the most important mechanism in the transmission of information through synapses, to a more general situation including also synaptic facilitation. Our study shows that: 1) facilitation enhances the detection of correlated signals arriving from a subset of presynaptic excitatory neurons, with different degrees of correlation among this subset, and 2) the presence of facilitation allows for a better detection of firing rate changes. Finally, we also observed that facilitation determines the existence of an optimal input frequency which allows the best performance for a wide (maximum) range of the neuron firing threshold. This optimal frequency can be controlled by means of facilitation parameters.
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"abstract": "Using a realistic model of activity dependent dynamical synapses and a\nstandard integrate and fire neuron model we study, both analytically and\nnumerically, the conditions in which a postsynaptic neuron efficiently detects\ntemporal coincidences of spikes arriving at certain frequency from N different\nafferents. We extend a previous work that only considers synaptic depression as\nthe most important mechanism in the transmission of information through\nsynapses, to a more general situation including also synaptic facilitation. Our\nstudy shows that: 1) facilitation enhances the detection of correlated signals\narriving from a subset of presynaptic excitatory neurons, with different\ndegrees of correlation among this subset, and 2) the presence of facilitation\nallows for a better detection of firing rate changes. Finally, we also observed\nthat facilitation determines the existence of an optimal input frequency which\nallows the best performance for a wide (maximum) range of the neuron firing\nthreshold. This optimal frequency can be controlled by means of facilitation\nparameters.",
"arxiv_id": "q-bio/0605006",
"authors": [
"Jorge F. Mejias",
"Joaquin J. Torres"
],
"categories": [
"q-bio.NC"
],
"title": "The role of synaptic facilitation in coincidence spike detection",
"url": "https://arxiv.org/abs/q-bio/0605006"
},
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