{
  "annotation_id": "f4073732-3c65-43bc-87a9-5ab81be5a5d2",
  "date_created": "2026-03-02T18:01:14.821000Z",
  "date_modified": "2026-03-02T18:01:14.821000Z",
  "file_hash": "109b8275aa2686c0160cbb7892fa5ce650c48f8a405ab90b74bf3cb9ae885991",
  "private": false,
  "record": {
    "abstract": "We present a multiscale approach to the modeling of polymer dynamics in the\npresence of a fluid solvent. The approach combines Langevin Molecular Dynamics\n(MD) techniques with a mesoscopic Lattice-Boltzmann (LB) method for the solvent\ndynamics. A unique feature of the present approach is that hydrodynamic\ninteractions between the solute macromolecule and the aqueous solvent are\nhandled explicitly, and yet in a computationally tractable way due to the dual\nparticle-field nature of the LB solver. The suitability of the present LB-MD\nmultiscale approach is demonstrated for the problem of polymer fast\ntranslocation through a nanopore. We also provide an interpretation of our\nresults in the context of DNA translocation through a nanopore, a problem that\nhas attracted much theoretical and experimental attention recently.",
    "arxiv_id": "physics/0701029",
    "authors": [
      "Maria G. Fyta",
      "Simone Melchionna",
      "Efthimios Kaxiras",
      "Sauro Succi"
    ],
    "categories": [
      "physics.bio-ph",
      "physics.comp-ph"
    ],
    "doi": "10.1137/060660576",
    "journal_ref": "Multiscale Modeling and Simulation, 5 (2006) 1156",
    "title": "Multiscale coupling of molecular dynamics and hydrodynamics: application   to DNA translocation through a nanopore",
    "url": "https://arxiv.org/abs/physics/0701029"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "437cd964-2b76-48a6-9ca4-f6b58b19d90a",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}