dorsal/arxiv
View SchemaCoupled dynamics of voltage and calcium in paced cardiac cells
| Authors | Yohannes Shiferaw, Daisuke Sato, Alain Karma |
|---|---|
| Categories | |
| ArXiv ID | physics/0405048 |
| URL | https://arxiv.org/abs/physics/0405048 |
| DOI | 10.1103/PhysRevE.71.021903 |
Abstract
We investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret various experimentally observed modes of instability ranging from electromechanically concordant and discordant alternans to quasiperiodic oscillations of voltage and calcium.
{
"annotation_id": "efd4b39e-8c8e-440a-8af3-5c9871b2e7fd",
"date_created": "2026-03-02T18:00:49.723000Z",
"date_modified": "2026-03-02T18:00:49.723000Z",
"file_hash": "d0061110848df34cdfdc75277a8bafd12afd726289008edd9fe1e747c1133d4a",
"private": false,
"record": {
"abstract": "We investigate numerically and analytically the coupled dynamics of\ntransmembrane voltage and intracellular calcium cycling in paced cardiac cells\nusing a detailed physiological model and its reduction to a three-dimensional\ndiscrete map. The results provide a theoretical framework to interpret various\nexperimentally observed modes of instability ranging from electromechanically\nconcordant and discordant alternans to quasiperiodic oscillations of voltage\nand calcium.",
"arxiv_id": "physics/0405048",
"authors": [
"Yohannes Shiferaw",
"Daisuke Sato",
"Alain Karma"
],
"categories": [
"physics.bio-ph"
],
"doi": "10.1103/PhysRevE.71.021903",
"title": "Coupled dynamics of voltage and calcium in paced cardiac cells",
"url": "https://arxiv.org/abs/physics/0405048"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "8665c6b8-26e2-4161-b35c-ce0381248428",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}