{
  "annotation_id": "efc2906f-49e4-4bbb-a607-b34455247710",
  "date_created": "2026-03-02T18:01:32.164000Z",
  "date_modified": "2026-03-02T18:01:32.164000Z",
  "file_hash": "df1d8a8e59164e04c2100a2b2bf1309cae15b3106f74919c7d51bdbdb4399a40",
  "private": false,
  "record": {
    "abstract": "We calculate the equation of state of DNA under tension for the case that the\nDNA features loops. Such loops occur transiently during DNA condensation in the\npresence of multivalent ions or sliding cationic protein linkers. The\nforce-extension relation of such looped DNA modelled as a wormlike chain is\ncalculated via path integration in the semiclassical limit. This allows us to\ndetermine rigorously the high stretching asymptotics. Notably the functional\nform of the force-extension curve resembles that of straight DNA, yet with a\nstrongly renormalized apparent persistence length. That means that the\nexperimentally extracted single molecule elasticity does not necessarily\nreflect the bare DNA stiffness only, but can also contain additional\ncontributions that depend on the overall chain conformation and length.",
    "arxiv_id": "q-bio/0509003",
    "authors": [
      "I. M. Kulic",
      "H. Mohrbach",
      "R. Thaokar",
      "H. Schiessel"
    ],
    "categories": [
      "q-bio.BM"
    ],
    "title": "Equation of state of looped DNA",
    "url": "https://arxiv.org/abs/q-bio/0509003"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "9b2c1616-4de6-4ec6-8f45-a2937620274f",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}