{
  "annotation_id": "ef97db7a-5997-4da6-bb43-0b1b87302843",
  "date_created": "2026-03-02T18:01:31.661000Z",
  "date_modified": "2026-03-02T18:01:31.661000Z",
  "file_hash": "38f48e22fabe32e9b49758c57a8d1887c745ab2e08bd6760fe78a60dc2e2d1f9",
  "private": false,
  "record": {
    "abstract": "This paper explores fluctuations and noise in various facets of cancer\ndevelopment. The three areas of particular focus are the stochastic progression\nof cells to cancer, fluctuations of the tumor size during treatment, and noise\nin cancer cell signalling. We explore the stochastic dynamics of tumor growth\nand response to treatment using a Markov model, and fluctutions in tumor size\nin response to treatment using partial differential equations. We also explore\nnoise within gene networks in cancer cells, and noise in inter-cell signalling.",
    "arxiv_id": "q-bio/0404009",
    "authors": [
      "Matthew J. Berryman",
      "Sabrina L. Spencer",
      "Andrew Allison",
      "Derek Abbott"
    ],
    "categories": [
      "q-bio.CB",
      "q-bio.MN"
    ],
    "doi": "10.1117/12.546641",
    "title": "Fluctuations and noise in cancer development",
    "url": "https://arxiv.org/abs/q-bio/0404009"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "f180e6d6-5f50-43ef-8625-33dfbfd4f2e5",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}