{
  "annotation_id": "ed42872d-24e0-4794-8e7c-fd6e6adeef77",
  "date_created": "2026-03-02T18:01:31.994000Z",
  "date_modified": "2026-03-02T18:01:31.994000Z",
  "file_hash": "426a1c05f74ae512830665299200fb2f3561c3b49fecbaf02ca71d28d541c9da",
  "private": false,
  "record": {
    "abstract": "Motivated by recent research of aging in E. coli, we explore the effects of\naging on bacterial fitness. The disposable soma theory of aging was developed\nto explain how differences in lifespans and aging rates could be linked to life\nhistory trade-offs. Although generally applied for multicellular organisms, it\nis also useful for exploring life history strategies of single celled organisms\nsuch as bacteria. Starting from the Euler-Lotka equation, we propose a\nmathematical model to explore how a finite lifespan effects fitness of\nbacteria. We find that that there is surprisingly little loss of fitness when\nthe bacterium has limited opportunities to reproduce. Instead, the fitness\ngained each time the bacteria reproduces decreases rapidly, and investing\nresources to survive to reproduce the first few times is likely more\nadvantageous than investing additional resources to try to maintain cell\nintegrity longer.",
    "arxiv_id": "q-bio/0510001",
    "authors": [
      "Leah R. Johnson",
      "Marc Mangel"
    ],
    "categories": [
      "q-bio.PE"
    ],
    "doi": "10.1016/j.mad.2006.07.004",
    "journal_ref": "Mech. Age. Dev., Vol 127/10 pp 786-793, 2006",
    "title": "Implications of Aging in Bacteria",
    "url": "https://arxiv.org/abs/q-bio/0510001"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "5e543e4a-5c1c-4f06-8fbc-f45b341727be",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}