dorsal/arxiv
View SchemaUniversal Mortality Law, Life Expectancy and Immortality
| Authors | Mark Ya. Azbel' |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0405025 |
| URL | https://arxiv.org/abs/q-bio/0405025 |
| DOI | 10.1016/j.physa.2004.06.065 |
Abstract
Well protected human and laboratory animal populations with abundant resources are evolutionary unprecedented, and their survival far beyond reproductive age may be a byproduct rather than tool of evolution. Physical approach, which takes advantage of their extensively quantified mortality, establishes that its dominant fraction yields the exact law, and suggests its unusual mechanism. The law is universal for all animals, from yeast to humans, despite their drastically different biology and evolution. It predicts that the universal mortality has short memory of the life history, at any age may be reset to its value at a significantly younger age, and mean life expectancy extended (by biologically unprecedented small changes) from its current maximal value to immortality. Mortality change is rapid and stepwise. Demographic data and recent experiments verify these predictions for humans, rats, flies, nematodes and yeast. In particular, mean life expectancy increased 6-fold (to "human" 430 years), with no apparent loss in health and vitality, in nematodes with a small number of perturbed genes and tissues. Universality allows one to study unusual mortality mechanism and the ways to immortality.
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"abstract": "Well protected human and laboratory animal populations with abundant\nresources are evolutionary unprecedented, and their survival far beyond\nreproductive age may be a byproduct rather than tool of evolution. Physical\napproach, which takes advantage of their extensively quantified mortality,\nestablishes that its dominant fraction yields the exact law, and suggests its\nunusual mechanism. The law is universal for all animals, from yeast to humans,\ndespite their drastically different biology and evolution. It predicts that the\nuniversal mortality has short memory of the life history, at any age may be\nreset to its value at a significantly younger age, and mean life expectancy\nextended (by biologically unprecedented small changes) from its current maximal\nvalue to immortality. Mortality change is rapid and stepwise. Demographic data\nand recent experiments verify these predictions for humans, rats, flies,\nnematodes and yeast. In particular, mean life expectancy increased 6-fold (to\n\"human\" 430 years), with no apparent loss in health and vitality, in nematodes\nwith a small number of perturbed genes and tissues. Universality allows one to\nstudy unusual mortality mechanism and the ways to immortality.",
"arxiv_id": "q-bio/0405025",
"authors": [
"Mark Ya. Azbel\u0027"
],
"categories": [
"q-bio.PE",
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"doi": "10.1016/j.physa.2004.06.065",
"title": "Universal Mortality Law, Life Expectancy and Immortality",
"url": "https://arxiv.org/abs/q-bio/0405025"
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