{
  "annotation_id": "e3a597ab-56e6-442c-8e19-a372d7d947dd",
  "date_created": "2026-03-02T18:01:32.238000Z",
  "date_modified": "2026-03-02T18:01:32.238000Z",
  "file_hash": "a0c33a425518880de80201c7abf1051fa725daca4b1a091cf53e5a7067fabea3",
  "private": false,
  "record": {
    "abstract": "We investigate a mechanism for the polar localization of proteins in\nbacteria. We focus on the MinCD/DivIVA system regulating division site\nplacement in the rod-shaped bacterium Bacillus subtilis. Our model relies on a\ncombination of geometric effects and reaction-diffusion dynamics to direct\nproteins to both cell poles, where division is then blocked. We discuss\nsimilarities and differences with related division models in Escherichia coli\nand also develop extensions of the model to asymmetric polar protein\nlocalization. We propose that our mechanism for polar localization may be\nemployed more widely in bacteria, especially in outgrowing spores, which do not\npossess any pre-existing polar division apparatus from prior division events.",
    "arxiv_id": "q-bio/0312015",
    "authors": [
      "Martin Howard"
    ],
    "categories": [
      "q-bio.SC",
      "cond-mat.soft"
    ],
    "journal_ref": "J. Mol. Biol. 335 655-663 (2004)",
    "title": "A mechanism for polar protein localization in bacteria",
    "url": "https://arxiv.org/abs/q-bio/0312015"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "43f475df-f9ea-4daf-ba00-8a8134e1678e",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}