dorsal/arxiv
View SchemaBroadband Relaxation-Optimized Polarization Transfer in Magnetic Resonance
| Authors | N. Khaneja, J. S. Li, C. Kehlet, B. Luy, S. J. Glaser |
|---|---|
| Categories | |
| ArXiv ID | quant-ph/0407178 |
| URL | https://arxiv.org/abs/quant-ph/0407178 |
Abstract
Many applications of magnetic resonance are limited by rapid loss of spin coherence caused by large transverse relaxation rates. In nuclear magnetic resonance (NMR) of large proteins, increased relaxation losses lead to poor sensitivity of experiments and increased measurement time. In this paper we develop broadband relaxation optimized pulse sequences (BB-CROP) which approach fundamental limits of coherence transfer efficiency in the presence of very general relaxation mechanisms that include cross-correlated relaxation. These broadband transfer schemes use new techniques of chemical shift refocusing (STAR echoes) that are tailored to specific trajectories of coupled spin evolution. We present simulations and experimental data indicating significant enhancement in the sensitivity of multi-dimensional NMR experiments of large molecules by use of these methods.
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"abstract": "Many applications of magnetic resonance are limited by rapid loss of spin\ncoherence caused by large transverse relaxation rates. In nuclear magnetic\nresonance (NMR) of large proteins, increased relaxation losses lead to poor\nsensitivity of experiments and increased measurement time. In this paper we\ndevelop broadband relaxation optimized pulse sequences (BB-CROP) which approach\nfundamental limits of coherence transfer efficiency in the presence of very\ngeneral relaxation mechanisms that include cross-correlated relaxation. These\nbroadband transfer schemes use new techniques of chemical shift refocusing\n(STAR echoes) that are tailored to specific trajectories of coupled spin\nevolution. We present simulations and experimental data indicating significant\nenhancement in the sensitivity of multi-dimensional NMR experiments of large\nmolecules by use of these methods.",
"arxiv_id": "quant-ph/0407178",
"authors": [
"N. Khaneja",
"J. S. Li",
"C. Kehlet",
"B. Luy",
"S. J. Glaser"
],
"categories": [
"quant-ph"
],
"title": "Broadband Relaxation-Optimized Polarization Transfer in Magnetic Resonance",
"url": "https://arxiv.org/abs/quant-ph/0407178"
},
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