dorsal/arxiv
View SchemaAn Analysis of the Thermodynamics of Hydrophobic Solvation Based on Scaled Particle Theory
| Authors | Hong Qian |
|---|---|
| Categories | |
| ArXiv ID | physics/0104085 |
| URL | https://arxiv.org/abs/physics/0104085 |
Abstract
A comprehensive, semi-quantitative model for the thermodynamics of hydrophobic solvation is presented. The model is based on a very simple premise suggested by the scaled particle theory and treats both solute and solvent molecules as hard spheres. A connection between the peculiarly large heat-capacity change for hydrophobic solvation and the large temperature dependence of the thermal expansivity of water is found. Analysis reveals a possible physical origin for the converging behavior of solvation entropies for a series of homologous hydrophobic compounds. The model suggests that the low solubility and the large heat-capacity change of hydrophobic solvation stem from two distinct aspects of water molecules: the static geometry of the molecule and the dynamic hydrogen bonding network, respectively.
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"date_created": "2026-03-02T18:00:36.355000Z",
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"abstract": "A comprehensive, semi-quantitative model for the thermodynamics of\nhydrophobic solvation is presented. The model is based on a very simple premise\nsuggested by the scaled particle theory and treats both solute and solvent\nmolecules as hard spheres. A connection between the peculiarly large\nheat-capacity change for hydrophobic solvation and the large temperature\ndependence of the thermal expansivity of water is found. Analysis reveals a\npossible physical origin for the converging behavior of solvation entropies for\na series of homologous hydrophobic compounds. The model suggests that the low\nsolubility and the large heat-capacity change of hydrophobic solvation stem\nfrom two distinct aspects of water molecules: the static geometry of the\nmolecule and the dynamic hydrogen bonding network, respectively.",
"arxiv_id": "physics/0104085",
"authors": [
"Hong Qian"
],
"categories": [
"physics.bio-ph",
"q-bio.BM"
],
"title": "An Analysis of the Thermodynamics of Hydrophobic Solvation Based on Scaled Particle Theory",
"url": "https://arxiv.org/abs/physics/0104085"
},
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