{
  "annotation_id": "dfa7256e-1a5c-45de-a788-744c7a076ff4",
  "date_created": "2026-03-02T18:01:34.731000Z",
  "date_modified": "2026-03-02T18:01:34.731000Z",
  "file_hash": "6030b07acecdd4979b09fe5910f4d0e1de208feb42e30f76ac91ecb72b963328",
  "private": false,
  "record": {
    "abstract": "The solubilizing power of various nonionic and zwitterionic detergents as\nmembrane protein solubilizers for two-dimensional electrophoresis was\ninvestigated. Human red blood cell ghosts and Arabidopsis thaliana leaf\nmembrane proteins were used as model systems. Efficient detergents could be\nfound in each class, i.e. with oligooxyethylene, sugar or sulfobetaine polar\nheads. Among the commercially available nonionic detergents, dodecyl maltoside\nand decaethylene glycol mono hexadecyl ether proved most efficient. They\ncomplement the more classical sulfobetaine detergents to widen the scope of\nuseful detergents for the solubilization of membrane proteins in proteomics.",
    "arxiv_id": "q-bio/0611076",
    "authors": [
      "Sylvie Luche",
      "V\u00e9ronique Santoni",
      "Thierry Rabilloud"
    ],
    "categories": [
      "q-bio.GN"
    ],
    "doi": "10.1002/pmic.200390037",
    "journal_ref": "Proteomics 3 (03/2003) 249-53",
    "title": "Evaluation of nonionic and zwitterionic detergents as membrane protein   solubilizers in two-dimensional electrophoresis",
    "url": "https://arxiv.org/abs/q-bio/0611076"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "04a91934-e2c3-41ca-bb26-bb717a7eb2e9",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}