{
  "annotation_id": "d9297896-ae1d-4286-a2f4-aa97deb53796",
  "date_created": "2026-03-02T18:01:31.480000Z",
  "date_modified": "2026-03-02T18:01:31.480000Z",
  "file_hash": "395d1096d369a24d43156455a1e7bfce8e9f8437ba898f4411184fb89a790d1c",
  "private": false,
  "record": {
    "abstract": "The response of the immune system to different vaccination patterns is\nstudied with a simple model. It is argued that the history and characteristics\nof the pattern defines very different secondary immune responses in the case of\ninfection. The memory function of the immune response can be set to work in\nvery different modes depending on the pattern followed during immunizations. It\nis argued that the history and pattern of immunizations can be a decisive (and\nexperimentally accessible) factor to tailor the effectiveness of a specific\nvaccine.",
    "arxiv_id": "q-bio/0407005",
    "authors": [
      "P. Etchegoin"
    ],
    "categories": [
      "q-bio.OT"
    ],
    "doi": "10.1016/j.physa.2005.02.041",
    "title": "Vaccination pattern affects immunological response",
    "url": "https://arxiv.org/abs/q-bio/0407005"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "31952aa4-bf22-44a3-a5ce-681439ebaf19",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}