dorsal/arxiv
View SchemaPhase transition in the collective migration of tissue cells: experiment and model
| Authors | Balint Szabo, Gergely J. Szollosi, Balazs Gonci, Zsofi Juranyi, David Selmeczi, Tamas Vicsek |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0611045 |
| URL | https://arxiv.org/abs/q-bio/0611045 |
| DOI | 10.1103/PhysRevE.74.061908 |
| Journal | Phys. Rev. E 74, 061908 (2006). |
Abstract
We have recorded the swarming-like collective migration of a large number of keratocytes (tissue cells obtained from the scales of goldfish) using long-term videomicroscopy. By increasing the overall density of the migrating cells, we have been able to demonstrate experimentally a kinetic phase transition from a disordered into an ordered state. Near the critical density a complex picture emerges with interacting clusters of cells moving in groups. Motivated by these experiments we have constructed a flocking model that exhibits a continuous transition to the ordered phase, while assuming only short-range interactions and no explicit information about the knowledge of the directions of motion of neighbors. Placing cells in microfabricated arenas we found spectacular whirling behavior which we could also reproduce in simulations.
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"abstract": "We have recorded the swarming-like collective migration of a large number of\nkeratocytes (tissue cells obtained from the scales of goldfish) using long-term\nvideomicroscopy. By increasing the overall density of the migrating cells, we\nhave been able to demonstrate experimentally a kinetic phase transition from a\ndisordered into an ordered state. Near the critical density a complex picture\nemerges with interacting clusters of cells moving in groups. Motivated by these\nexperiments we have constructed a flocking model that exhibits a continuous\ntransition to the ordered phase, while assuming only short-range interactions\nand no explicit information about the knowledge of the directions of motion of\nneighbors. Placing cells in microfabricated arenas we found spectacular\nwhirling behavior which we could also reproduce in simulations.",
"arxiv_id": "q-bio/0611045",
"authors": [
"Balint Szabo",
"Gergely J. Szollosi",
"Balazs Gonci",
"Zsofi Juranyi",
"David Selmeczi",
"Tamas Vicsek"
],
"categories": [
"q-bio.CB",
"cond-mat.stat-mech",
"physics.bio-ph",
"q-bio.QM",
"q-bio.TO"
],
"doi": "10.1103/PhysRevE.74.061908",
"journal_ref": "Phys. Rev. E 74, 061908 (2006).",
"title": "Phase transition in the collective migration of tissue cells: experiment and model",
"url": "https://arxiv.org/abs/q-bio/0611045"
},
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