{
  "annotation_id": "d0ffcc6a-e4b1-405b-8ad1-892bb0a47828",
  "date_created": "2026-03-02T18:00:36.339000Z",
  "date_modified": "2026-03-02T18:00:36.339000Z",
  "file_hash": "e86ca558951333559bf9c4b15b5b61767d557fd3cc2de1e2ab9bb16f706fa4e9",
  "private": false,
  "record": {
    "abstract": "Ice formation in model biological membranes is studied by SAXS and WAXS in\nthe presence of cryoprotectors: dimethyl sulfoxide and glycerol. Three types of\nphospholipid membranes: DPPC, DMPC, DSPC are chosen for the investigation as\nwell-studied model biological membranes. A special cryostat is used for sample\ncooling from 14.1C to -55.4C. The ice formation is only detected by WAXS in\nbinary phospholipid/water and ternary phospholipid/cryoprotector/water systems\nin the condition of excess solvent. Ice formation in a binary\nphospholipid/water system creates an abrupt decrease of the membrane repeat\ndistance by delta-d, so-called ice-induced dehydration of intermembrane space.\nThe value of delta-d decreases as the cryoprotector concentration increases.\nThe formation of ice does not influence the membrane structure (delta-d = 0)\nfor cryoprotector mole fractions higher than 0.05.",
    "arxiv_id": "physics/0108023",
    "authors": [
      "M. A. Kiselev",
      "P. Lesieur",
      "A. M. Kisselev",
      "M. Ollivon"
    ],
    "categories": [
      "physics.bio-ph",
      "cond-mat.soft",
      "physics.chem-ph",
      "physics.med-ph"
    ],
    "doi": "10.1016/S0168-9002(99)00730-5",
    "journal_ref": "Nuclear Instruments \u0026 Methods in Physics Research A 448 (2000)\n  225-260",
    "title": "Ice Formation in Model Biological Membranes in the Presence of   Cryoprotectors",
    "url": "https://arxiv.org/abs/physics/0108023"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "dde75730-2c69-49c2-a423-81b80d6810e6",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}