{
  "annotation_id": "ce976f3d-5130-49b7-9108-2e2d6b119810",
  "date_created": "2026-03-02T18:01:35.814000Z",
  "date_modified": "2026-03-02T18:01:35.814000Z",
  "file_hash": "03322db1b9cf0134a015350f8c849fb7840ff544fe5ae27338b5c1ad0738dff8",
  "private": false,
  "record": {
    "abstract": "Competition within the immune system may degrade immune control of viral\ninfections. We formalize the evolution that occurs in both HIV-1 and the immune\nsystem quasispecies. Inclusion of competition in the immune system leads to a\nnovel balance between the immune response and HIV-1, in which the eventual\noutcome is HIV-1 escape rather than control. The analytical model reproduces\nthe three stages of HIV-1 infection. We propose a vaccine regimen that may be\nable to reduce competition between T cells, potentially eliminating the third\nstage of HIV-1.",
    "arxiv_id": "q-bio/0610018",
    "authors": [
      "Guanyu Wang",
      "Michael W. Deem"
    ],
    "categories": [
      "q-bio.PE"
    ],
    "doi": "10.1103/PhysRevLett.97.188106",
    "title": "A Physical Theory of the Competition that Allows HIV to Escape from the   Immune System",
    "url": "https://arxiv.org/abs/q-bio/0610018"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "6cd9e749-8e87-43da-a1af-f0d0f0384a70",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}