dorsal/arxiv
View SchemaUni-directional polymerization leading to homochirality in the RNA world
| Authors | M. Nilsson, A. Brandenburg, A. C. Andersen, S. Hoefner |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0505041 |
| URL | https://arxiv.org/abs/q-bio/0505041 |
| DOI | 10.1017/S1473550405002752 |
| Journal | Int. J. Astrobiology 4, 233-239 (2005) |
Abstract
The differences between uni-directional and bi-directional polymerization are considered. The uni-directional case is discussed in the framework of the RNA world. Similar to earlier models of this type, where polymerization was assumed to proceed in a bi-directional fashion (presumed to be relevant to peptide nucleic acids), left-handed and right-handed monomers are produced via an autocatalysis from an achiral substrate. The details of the bifurcation from a racemic solution to a homochiral state of either handedness is shown to be remarkably independent of whether the polymerization in uni-directional or bi-directional. Slightly larger differences are seen when dissociation is allowed and the dissociation fragments are being recycled into the achiral substrate.
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"abstract": "The differences between uni-directional and bi-directional polymerization are\nconsidered. The uni-directional case is discussed in the framework of the RNA\nworld. Similar to earlier models of this type, where polymerization was assumed\nto proceed in a bi-directional fashion (presumed to be relevant to peptide\nnucleic acids), left-handed and right-handed monomers are produced via an\nautocatalysis from an achiral substrate. The details of the bifurcation from a\nracemic solution to a homochiral state of either handedness is shown to be\nremarkably independent of whether the polymerization in uni-directional or\nbi-directional. Slightly larger differences are seen when dissociation is\nallowed and the dissociation fragments are being recycled into the achiral\nsubstrate.",
"arxiv_id": "q-bio/0505041",
"authors": [
"M. Nilsson",
"A. Brandenburg",
"A. C. Andersen",
"S. Hoefner"
],
"categories": [
"q-bio.BM"
],
"doi": "10.1017/S1473550405002752",
"journal_ref": "Int. J. Astrobiology 4, 233-239 (2005)",
"title": "Uni-directional polymerization leading to homochirality in the RNA world",
"url": "https://arxiv.org/abs/q-bio/0505041"
},
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