{
  "annotation_id": "c6c34f01-beb7-4da3-9bc6-9a5e3846bd62",
  "date_created": "2026-03-02T18:01:32.169000Z",
  "date_modified": "2026-03-02T18:01:32.169000Z",
  "file_hash": "a1c23d443551f99873ca3a9e546ea85781b081c289a029cc874028cb049d1cda",
  "private": false,
  "record": {
    "abstract": "The differences between uni-directional and bi-directional polymerization are\nconsidered. The uni-directional case is discussed in the framework of the RNA\nworld. Similar to earlier models of this type, where polymerization was assumed\nto proceed in a bi-directional fashion (presumed to be relevant to peptide\nnucleic acids), left-handed and right-handed monomers are produced via an\nautocatalysis from an achiral substrate. The details of the bifurcation from a\nracemic solution to a homochiral state of either handedness is shown to be\nremarkably independent of whether the polymerization in uni-directional or\nbi-directional. Slightly larger differences are seen when dissociation is\nallowed and the dissociation fragments are being recycled into the achiral\nsubstrate.",
    "arxiv_id": "q-bio/0505041",
    "authors": [
      "M. Nilsson",
      "A. Brandenburg",
      "A. C. Andersen",
      "S. Hoefner"
    ],
    "categories": [
      "q-bio.BM"
    ],
    "doi": "10.1017/S1473550405002752",
    "journal_ref": "Int. J. Astrobiology 4, 233-239 (2005)",
    "title": "Uni-directional polymerization leading to homochirality in the RNA world",
    "url": "https://arxiv.org/abs/q-bio/0505041"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "fde56124-837d-42df-9122-30886c1d6e12",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}