{
  "annotation_id": "c6affc72-bc75-4d7c-9339-1ab788c54439",
  "date_created": "2026-03-02T18:01:35.330000Z",
  "date_modified": "2026-03-02T18:01:35.330000Z",
  "file_hash": "2f25a333fbb44c137f4cdce790c1b194af1e49f9a4d503f29c429bb0ffa955eb",
  "private": false,
  "record": {
    "abstract": "Dynamical wiring and rewiring in neural networks are carried out by\nactivity-dependent growth and retraction of axons and dendrites, guided by\ngudance molecules, released by target cells. Experience-dependent structural\nchanges in cortical microcurcuts lead to changes in activity, i.e. to changes\nin information encoded. Specific pattens of external stimulation can lead to\ncreation of new synaptical connections between neurons. Calcium influxes\ncontrolled by neuronal activity regulates processes of neurotrophic factors\nrelease by neurons, growth cones movement and synapse differentiation in\ndeveloping neural system, therefore activity-dependent self-wiring can serve as\na basis of structural plasticity in cortical networks and can be considered as\na form of learning.",
    "arxiv_id": "q-bio/0607021",
    "authors": [
      "Fail M. Gafarov"
    ],
    "categories": [
      "q-bio.NC"
    ],
    "title": "Activity-dependent self-wiring is a basis of structural plastisity in   neural networks",
    "url": "https://arxiv.org/abs/q-bio/0607021"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "2fbba09a-8103-40dd-a700-eee353eead1c",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}