dorsal/arxiv
View SchemaSpectral Analysis of Protein-Protein Interactions in Drosophila melanogaster
| Authors | Christel Kamp, Kim Christensen |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0405021 |
| URL | https://arxiv.org/abs/q-bio/0405021 |
| DOI | 10.1103/PhysRevE.71.041911 |
Abstract
Within a case study on the protein-protein interaction network (PIN) of Drosophila melanogaster we investigate the relation between the network's spectral properties and its structural features such as the prevalence of specific subgraphs or duplicate nodes as a result of its evolutionary history. The discrete part of the spectral density shows fingerprints of the PIN's topological features including a preference for loop structures. Duplicate nodes are another prominent feature of PINs and we discuss their representation in the PIN's spectrum as well as their biological implications.
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"abstract": "Within a case study on the protein-protein interaction network (PIN) of\nDrosophila melanogaster we investigate the relation between the network\u0027s\nspectral properties and its structural features such as the prevalence of\nspecific subgraphs or duplicate nodes as a result of its evolutionary history.\nThe discrete part of the spectral density shows fingerprints of the PIN\u0027s\ntopological features including a preference for loop structures. Duplicate\nnodes are another prominent feature of PINs and we discuss their representation\nin the PIN\u0027s spectrum as well as their biological implications.",
"arxiv_id": "q-bio/0405021",
"authors": [
"Christel Kamp",
"Kim Christensen"
],
"categories": [
"q-bio.MN",
"cond-mat.stat-mech"
],
"doi": "10.1103/PhysRevE.71.041911",
"title": "Spectral Analysis of Protein-Protein Interactions in Drosophila melanogaster",
"url": "https://arxiv.org/abs/q-bio/0405021"
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