dorsal/arxiv
View SchemaBrownian Dynamics Simulation of Nucleosome Formation and Disruption under Stretching
| Authors | Wei Li, Shuo-Xing Dou, Peng-Ye Wang |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0312036 |
| URL | https://arxiv.org/abs/q-bio/0312036 |
| Journal | Journal of Theoretical Biology 230 (2004) 375-383 |
Abstract
Using a Brownian dynamics simulation, we numerically studied the interaction of DNA with histone and proposed an octamer-rotation model to describe the process of nucleosome formation. Nucleosome disruption under stretching was also simulated. The theoretical curves of extension versus time as well as of force versus extension are consistent with previous experimental results.
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"abstract": "Using a Brownian dynamics simulation, we numerically studied the interaction\nof DNA with histone and proposed an octamer-rotation model to describe the\nprocess of nucleosome formation. Nucleosome disruption under stretching was\nalso simulated. The theoretical curves of extension versus time as well as of\nforce versus extension are consistent with previous experimental results.",
"arxiv_id": "q-bio/0312036",
"authors": [
"Wei Li",
"Shuo-Xing Dou",
"Peng-Ye Wang"
],
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"q-bio.BM"
],
"journal_ref": "Journal of Theoretical Biology 230 (2004) 375-383",
"title": "Brownian Dynamics Simulation of Nucleosome Formation and Disruption under Stretching",
"url": "https://arxiv.org/abs/q-bio/0312036"
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