dorsal/arxiv
View SchemaDynamics of conduction blocks in a model of paced cardiac tissue
| Authors | Herve Henry, Wouter-Jan Rappel |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0504009 |
| URL | https://arxiv.org/abs/q-bio/0504009 |
| DOI | 10.1103/PhysRevE.71.051911 |
Abstract
We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region. Small pacing regions lead to stationary conduction blocks while larger pacing regions can lead to conduction blocks that travel periodically towards the pacing region. We show that this size-dependence dynamics can lead to a novel arrhythmogenic mechanism. Furthermore, we show that the essential phenomena can be captured in a much simpler coupled-map model.
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"abstract": "We study numerically the dynamics of conduction blocks using a detailed\nelectrophysiological model. We find that this dynamics depends critically on\nthe size of the paced region. Small pacing regions lead to stationary\nconduction blocks while larger pacing regions can lead to conduction blocks\nthat travel periodically towards the pacing region. We show that this\nsize-dependence dynamics can lead to a novel arrhythmogenic mechanism.\nFurthermore, we show that the essential phenomena can be captured in a much\nsimpler coupled-map model.",
"arxiv_id": "q-bio/0504009",
"authors": [
"Herve Henry",
"Wouter-Jan Rappel"
],
"categories": [
"q-bio.TO",
"cond-mat.other",
"nlin.PS",
"physics.bio-ph",
"q-bio.OT"
],
"doi": "10.1103/PhysRevE.71.051911",
"title": "Dynamics of conduction blocks in a model of paced cardiac tissue",
"url": "https://arxiv.org/abs/q-bio/0504009"
},
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