{
  "annotation_id": "bb964e5f-2173-4c85-8494-b3cde3c08f81",
  "date_created": "2026-03-02T18:01:35.859000Z",
  "date_modified": "2026-03-02T18:01:35.859000Z",
  "file_hash": "4a757e4477f1f1a32dd35aa9400504baa0463474f0825d34478846fed31c80a8",
  "private": false,
  "record": {
    "abstract": "Mechanosensation is a key part of the sensory repertoire of a vast array of\ndifferent cells and organisms. The molecular dissection of the origins of\nmechanosensation is rapidly advancing as a result of both structural and\nfunctional studies. One intriguing mode of mechanosensation results from\ntension in the membrane of the cell (or vesicle) of interest. The aim of this\nreview is to catalogue recent work that uses a mix of continuum and statistical\nmechanics to explore the role of the lipid bilayer in the function of\nmechanosensitive channels that respond to membrane tension. The role of bilayer\ndeformation will be explored in the context of the well known mechanosensitive\nchannel MscL. Additionally, we make suggestions for bridging gaps between our\ncurrent theoretical understanding and common experimental techniques.",
    "arxiv_id": "q-bio/0702030",
    "authors": [
      "Tristan Ursell",
      "Rob Phillips",
      "Jane\u0027 Kondev",
      "Dan Reeves",
      "Paul A. Wiggins"
    ],
    "categories": [
      "q-bio.SC",
      "q-bio.QM"
    ],
    "title": "The Role of Lipid Bilayer Mechanics in Mechanosensation",
    "url": "https://arxiv.org/abs/q-bio/0702030"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "7228e132-37b5-42c0-86e7-bafa2127b3c8",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}