dorsal/arxiv
View SchemaDiscovery and analysis of biochemical subnetwork hierarchies
| Authors | Petter Holme, Mikael Huss |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0309011 |
| URL | https://arxiv.org/abs/q-bio/0309011 |
| Journal | 3rd Workshop on Computation of Biochemical Pathways and Genetic Networks, R. Gauges, U. Kummer, J. Pahle, and U. Rost, eds., European Media Lab Proceedings (Logos, Berlin, 2003), pp. 3-9. |
Abstract
The representation of a biochemical network as a graph is the coarsest level of description in cellular biochemistry. By studying the network structure one can draw conclusions on the large scale organisation of the biochemical processes. We describe methods how one can extract hierarchies of subnetworks, how these can be interpreted and further deconstructed to find autonomous subnetworks. The large-scale organisation we find is characterised by a tightly connected core surrounded by increasingly loosely connected substrates.
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"abstract": "The representation of a biochemical network as a graph is the coarsest level\nof description in cellular biochemistry. By studying the network structure one\ncan draw conclusions on the large scale organisation of the biochemical\nprocesses. We describe methods how one can extract hierarchies of subnetworks,\nhow these can be interpreted and further deconstructed to find autonomous\nsubnetworks. The large-scale organisation we find is characterised by a tightly\nconnected core surrounded by increasingly loosely connected substrates.",
"arxiv_id": "q-bio/0309011",
"authors": [
"Petter Holme",
"Mikael Huss"
],
"categories": [
"q-bio.MN",
"cond-mat.dis-nn"
],
"journal_ref": "3rd Workshop on Computation of Biochemical Pathways and Genetic\n Networks, R. Gauges, U. Kummer, J. Pahle, and U. Rost, eds., European Media\n Lab Proceedings (Logos, Berlin, 2003), pp. 3-9.",
"title": "Discovery and analysis of biochemical subnetwork hierarchies",
"url": "https://arxiv.org/abs/q-bio/0309011"
},
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