{
  "annotation_id": "aed54f5a-27bb-40bc-adb3-1b98e60830e8",
  "date_created": "2026-03-02T18:01:11.219000Z",
  "date_modified": "2026-03-02T18:01:11.219000Z",
  "file_hash": "d83da2ef793132179fa61f03bc4ccc4942686da8bc78fd98bdd6fbdc77e1b025",
  "private": false,
  "record": {
    "abstract": "Dynamical instrument limitations, such as finite detection bandwidth, do not\nsimply add statistical errors to fluctuation measurements, but can create\nsignificant systematic biases that affect the measurement of steady-state\nproperties. Such effects must be considered when calibrating ultra-sensitive\nforce probes by analyzing the observed Brownian fluctuations. In this article,\nwe present a novel method for extracting the true spring constant and diffusion\ncoefficient of a harmonically confined Brownian particle that extends the\nstandard equipartition and power spectrum techniques to account for video-image\nmotion blur. These results are confirmed both numerically with a Brownian\ndynamics simulation, and experimentally with laser optical tweezers.",
    "arxiv_id": "physics/0607156",
    "authors": [
      "Wesley P. Wong",
      "Ken Halvorsen"
    ],
    "categories": [
      "physics.bio-ph",
      "physics.ins-det",
      "physics.optics"
    ],
    "doi": "10.1364/OE.14.012517",
    "journal_ref": "Opt.Express 14:12517-12531,2006",
    "title": "The effect of integration time on fluctuation measurements: calibrating   an optical trap in the presence of motion blur",
    "url": "https://arxiv.org/abs/physics/0607156"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "dc7f3820-c7ef-4b66-acfe-c40725f727df",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}