dorsal/arxiv
View SchemaJohnson-Kendall-Roberts theory applied to living cells
| Authors | Yeh-Shiu Chu, Sylvie Dufour, Jean Paul Thiery, Eric Perez, Frédéric Pincet |
|---|---|
| Categories | |
| ArXiv ID | physics/0510016 |
| URL | https://arxiv.org/abs/physics/0510016 |
| DOI | 10.1103/PhysRevLett.94.028102 |
| Journal | Physical Review Letters 94 (2005) 028102-1 |
Abstract
Johnson-Kendall-Roberts (JKR) theory is an accurate model for strong adhesion energies of soft slightly deformable material. Little is known about the validity of this theory on complex systems such as living cells. We have addressed this problem using a depletion controlled cell adhesion and measured the force necessary to separate the cells with a micropipette technique. We show that the cytoskeleton can provide the cells with a 3D structure that is sufficiently elastic and has a sufficiently low deformability for JKR theory to be valid. When the cytoskeleton is disrupted, JKR theory is no longer applicable.
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"abstract": "Johnson-Kendall-Roberts (JKR) theory is an accurate model for strong adhesion\nenergies of soft slightly deformable material. Little is known about the\nvalidity of this theory on complex systems such as living cells. We have\naddressed this problem using a depletion controlled cell adhesion and measured\nthe force necessary to separate the cells with a micropipette technique. We\nshow that the cytoskeleton can provide the cells with a 3D structure that is\nsufficiently elastic and has a sufficiently low deformability for JKR theory to\nbe valid. When the cytoskeleton is disrupted, JKR theory is no longer\napplicable.",
"arxiv_id": "physics/0510016",
"authors": [
"Yeh-Shiu Chu",
"Sylvie Dufour",
"Jean Paul Thiery",
"Eric Perez",
"Fr\u00e9d\u00e9ric Pincet"
],
"categories": [
"physics.bio-ph"
],
"doi": "10.1103/PhysRevLett.94.028102",
"journal_ref": "Physical Review Letters 94 (2005) 028102-1",
"title": "Johnson-Kendall-Roberts theory applied to living cells",
"url": "https://arxiv.org/abs/physics/0510016"
},
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