{
  "annotation_id": "a9f76cd1-d59a-4cf7-aea7-b3ed06c28234",
  "date_created": "2026-03-02T18:01:34.679000Z",
  "date_modified": "2026-03-02T18:01:34.679000Z",
  "file_hash": "a09348cc105b62c72c03fa7c0e1254593cb70021acea8683250d379419312d13",
  "private": false,
  "record": {
    "abstract": "The formation of DNA loops by proteins and protein complexes is ubiquitous to\nmany fundamental cellular processes, including transcription, recombination,\nand replication. Here we review recent advances in understanding the properties\nof DNA looping in its natural context and how they propagate to the cellular\nbehavior through gene regulation. The results of connecting the molecular\nproperties with cellular physiology indicate that looping of DNA in vivo is\nmuch more complex and easier than predicted from current models and reveals a\nwealth of previously unappreciated details.",
    "arxiv_id": "q-bio/0609045",
    "authors": [
      "Leonor Saiz",
      "Jose M. G. Vilar"
    ],
    "categories": [
      "q-bio.BM",
      "cond-mat.soft",
      "physics.bio-ph",
      "q-bio.SC"
    ],
    "doi": "10.1016/j.sbi.2006.05.008",
    "journal_ref": "Curr. Opin. Struct. Biol. 16, 344-350 (2006)",
    "title": "DNA looping: the consequences and its control",
    "url": "https://arxiv.org/abs/q-bio/0609045"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "19644284-2b73-4e12-8062-98d2d7ddfdfc",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}