dorsal/arxiv
View SchemaDNA looping: the consequences and its control
| Authors | Leonor Saiz, Jose M. G. Vilar |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0609045 |
| URL | https://arxiv.org/abs/q-bio/0609045 |
| DOI | 10.1016/j.sbi.2006.05.008 |
| Journal | Curr. Opin. Struct. Biol. 16, 344-350 (2006) |
Abstract
The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication. Here we review recent advances in understanding the properties of DNA looping in its natural context and how they propagate to the cellular behavior through gene regulation. The results of connecting the molecular properties with cellular physiology indicate that looping of DNA in vivo is much more complex and easier than predicted from current models and reveals a wealth of previously unappreciated details.
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"abstract": "The formation of DNA loops by proteins and protein complexes is ubiquitous to\nmany fundamental cellular processes, including transcription, recombination,\nand replication. Here we review recent advances in understanding the properties\nof DNA looping in its natural context and how they propagate to the cellular\nbehavior through gene regulation. The results of connecting the molecular\nproperties with cellular physiology indicate that looping of DNA in vivo is\nmuch more complex and easier than predicted from current models and reveals a\nwealth of previously unappreciated details.",
"arxiv_id": "q-bio/0609045",
"authors": [
"Leonor Saiz",
"Jose M. G. Vilar"
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"doi": "10.1016/j.sbi.2006.05.008",
"journal_ref": "Curr. Opin. Struct. Biol. 16, 344-350 (2006)",
"title": "DNA looping: the consequences and its control",
"url": "https://arxiv.org/abs/q-bio/0609045"
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