dorsal/arxiv
View SchemaStatistics of selectively neutral genetic variation
| Authors | A. Eriksson, B. Haubold, B. Mehlig |
|---|---|
| Categories | |
| ArXiv ID | physics/0111205 |
| URL | https://arxiv.org/abs/physics/0111205 |
| DOI | 10.1103/PhysRevE.65.040901 |
| Journal | Phys. Rev. E 65, 040901 (2002) |
Abstract
Random models of evolution are instrumental in extracting rates of microscopic evolutionary mechanisms from empirical observations on genetic variation in genome sequences. In this context it is necessary to know the statistical properties of empirical observables (such as the local homozygosity for instance). Previous work relies on numerical results or assumes Gaussian approximations for the corresponding distributions. In this paper we give an analytical derivation of the statistical properties of the local homozygosity and other empirical observables assuming selective neutrality. We find that such distributions can be very non-Gaussian.
{
"annotation_id": "a947a019-4618-4bed-b225-dc12219f6747",
"date_created": "2026-03-02T18:00:36.468000Z",
"date_modified": "2026-03-02T18:00:36.468000Z",
"file_hash": "b8f47573f68524de9e08fffe35097f596e9e1d0b2eb0a72197a6f86b96377158",
"private": false,
"record": {
"abstract": "Random models of evolution are instrumental in extracting rates of\nmicroscopic evolutionary mechanisms from empirical observations on genetic\nvariation in genome sequences. In this context it is necessary to know the\nstatistical properties of empirical observables (such as the local homozygosity\nfor instance). Previous work relies on numerical results or assumes Gaussian\napproximations for the corresponding distributions. In this paper we give an\nanalytical derivation of the statistical properties of the local homozygosity\nand other empirical observables assuming selective neutrality. We find that\nsuch distributions can be very non-Gaussian.",
"arxiv_id": "physics/0111205",
"authors": [
"A. Eriksson",
"B. Haubold",
"B. Mehlig"
],
"categories": [
"physics.bio-ph",
"q-bio.PE"
],
"doi": "10.1103/PhysRevE.65.040901",
"journal_ref": "Phys. Rev. E 65, 040901 (2002)",
"title": "Statistics of selectively neutral genetic variation",
"url": "https://arxiv.org/abs/physics/0111205"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "2ec230df-f40d-4009-b6dd-02478b235d39",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}