{
  "annotation_id": "a5e19db7-613b-40e4-9fb7-576d77ad8074",
  "date_created": "2026-03-02T18:00:46.919000Z",
  "date_modified": "2026-03-02T18:00:46.919000Z",
  "file_hash": "54fdec25879d8b60a3fbb26b9b0936f65fd31e24a03509234f1f2300953d286f",
  "private": false,
  "record": {
    "abstract": "The electropermeabilization of biological cell membranes by the application\nof an external field occurs whenever an applied field exceeds a threshold\nvalue. For fields above this threshold value but less than another critical\nvalue, the pores formed in the membrane are transient or reversible. Several\nmechanisms have been proposed for the formation of these transient pores. Here\nwe examine the local electric fields generated for the configuration of cells\nembedded in a polycarbonate filter, both in the region in and around the pore.\nWe consider the shear forces created in the membrane due to the gradient of the\nfield along the surface of the membrane, and the interaction of the charged\nmolecules in the membrane with this field. A relationship between the electric\nfield strength and the size of the pore formed is derived.",
    "arxiv_id": "physics/0308015",
    "authors": [
      "William A. Hercules",
      "James Lindesay",
      "Anna Coble",
      "Robert Schmukler"
    ],
    "categories": [
      "physics.bio-ph",
      "q-bio.QM"
    ],
    "title": "Electroporation of Biological Cells Embedded in a Polycarbonate Filter",
    "url": "https://arxiv.org/abs/physics/0308015"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "ee1ada72-411e-4cf2-961a-fdd4b173fd46",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}