{
  "annotation_id": "a54567d7-00c3-48e9-9287-1ee6a471ca57",
  "date_created": "2026-03-02T18:00:43.263000Z",
  "date_modified": "2026-03-02T18:00:43.263000Z",
  "file_hash": "6fc02c9b3735bb9b40535fbfde70cdff1a01d6d28acbd025bdb25ee07a03d69a",
  "private": false,
  "record": {
    "abstract": "We study the competition between several advantageous mutants in an asexual\npopulation (clonal interference) as a function of the time between the\nappearance of the mutants, their selective advantages, and the rate of\ndeleterious mutations. We find that the overall probability of fixation (the\nprobability that at least one of the mutants becomes the ancestor of the entire\npopulation) does not depend on the time interval between the appearance of\nthese mutants, and equals the probability that a genotype bearing all of these\nmutations reaches fixation. This result holds also in the presence of\ndeleterious mutations, and for an arbitrary number of competing mutants. We\nalso show that if mutations interfere, an increase in the mean number of\nfixation events is associated with a decrease in the expected fitness gain of\nthe population.",
    "arxiv_id": "physics/0305001",
    "authors": [
      "Paulo R. A. Campos",
      "Christoph Adami",
      "Claus O. Wilke"
    ],
    "categories": [
      "physics.bio-ph",
      "q-bio.PE"
    ],
    "title": "Modeling stochastic clonal interference",
    "url": "https://arxiv.org/abs/physics/0305001"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "384486db-fe04-42f3-b3a1-d0365866835d",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}