{
  "annotation_id": "a24411dd-cfba-4a46-9016-0d3d03c4fb3c",
  "date_created": "2026-03-02T18:01:35.460000Z",
  "date_modified": "2026-03-02T18:01:35.460000Z",
  "file_hash": "a182b9374c2393e0bcdbe58d1ad3441b3c6c001ded6bff4fa88ab934a6eb01a9",
  "private": false,
  "record": {
    "abstract": "The chiral nature of DNA plays a crucial role in cellular processes. Here we\nuse magnetic tweezers to explore one of the signatures of this chirality, the\ncoupling between stretch and twist deformations. We show that the extension of\na stretched DNA molecule increases linearly by 0.42 nm per excess turn applied\nto the double helix. This result contradicts the intuition that DNA should\nlengthen as it is unwound and get shorter with overwinding. We then present\nnumerical results of energy minimizations of torsionally restrained DNA that\ndisplay a behaviour similar to the experimental data and shed light on the\nmolecular details of this surprising effect.",
    "arxiv_id": "q-bio/0602008",
    "authors": [
      "Timothee Lionnet",
      "Sylvain Joubaud",
      "Richard Lavery",
      "David Bensimon",
      "Vincent Croquette"
    ],
    "categories": [
      "q-bio.BM"
    ],
    "doi": "10.1103/PhysRevLett.96.178102",
    "journal_ref": "Phys. Rev. Lett. 96 178102 (2006)",
    "title": "Wringing out DNA",
    "url": "https://arxiv.org/abs/q-bio/0602008"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "f9ad45fa-f0eb-47e4-98e2-564751881091",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}