dorsal/arxiv
View SchemaDynamic stability of spindles controlled by molecular motor kinetics
| Authors | Otger Campas, Jaume Casademunt, Ignacio Pagonabarraga |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0603036 |
| URL | https://arxiv.org/abs/q-bio/0603036 |
Abstract
We analyze the role of the force-dependent kinetics of motor proteins in the stability of antiparallel arrays of polar filaments, such as those in the mitotic spindle. We determine the possible stable structures and show that there exists an instability associated to the collective behavior of motors that leads to the collapse of the spindle. Our analysis provides a general framework to understand several experimental observations in eukaryotic cell division.
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"abstract": "We analyze the role of the force-dependent kinetics of motor proteins in the\nstability of antiparallel arrays of polar filaments, such as those in the\nmitotic spindle. We determine the possible stable structures and show that\nthere exists an instability associated to the collective behavior of motors\nthat leads to the collapse of the spindle. Our analysis provides a general\nframework to understand several experimental observations in eukaryotic cell\ndivision.",
"arxiv_id": "q-bio/0603036",
"authors": [
"Otger Campas",
"Jaume Casademunt",
"Ignacio Pagonabarraga"
],
"categories": [
"q-bio.SC",
"physics.bio-ph"
],
"title": "Dynamic stability of spindles controlled by molecular motor kinetics",
"url": "https://arxiv.org/abs/q-bio/0603036"
},
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