{
  "annotation_id": "9c0ff5ba-6ea8-41c6-ab39-c3113ab5946b",
  "date_created": "2026-03-02T18:01:31.819000Z",
  "date_modified": "2026-03-02T18:01:31.819000Z",
  "file_hash": "1972358681dfc566b8da564ea6f2b96cfc992a098c76bd0e27235c58f77c7d55",
  "private": false,
  "record": {
    "abstract": "In this letter we study the full semi-conservative treatment of a model for\nthe co-evolution of a virus and an adaptive immune system. Regions of viability\nare calculated for both conservatively and semi-conservatively replicating\nviruses interacting with a realistic semi-conservatively replicating immune\nsystem. The conservative virus is found to have a selective advantage in the\nform of an ability to survive in regions with a wider range of mutation rates\nthan its semi-conservative counterpart. This may help explain the existence of\na rich range of viruses with conservatively replicating genomes, a trait which\nis found nowhere else in nature.",
    "arxiv_id": "q-bio/0401022",
    "authors": [
      "Yisroel Brumer",
      "Eugene I. Shakhnovich"
    ],
    "categories": [
      "q-bio.PE",
      "cond-mat.soft"
    ],
    "doi": "10.1103/PhysRevE.71.031903",
    "title": "A Selective Advantage for Conservative Viruses",
    "url": "https://arxiv.org/abs/q-bio/0401022"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "d7b7343f-33bb-4153-84ed-ea7a0fa862e5",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}