dorsal/arxiv
View SchemaClose contact fluctuations: the seeding of signalling domains in the immunological synapse
| Authors | Amit K Chattopadhyay, Nigel J Burroughs |
|---|---|
| Categories | |
| ArXiv ID | physics/0612142 |
| URL | https://arxiv.org/abs/physics/0612142 |
| DOI | 10.1209/0295-5075/77/48003 |
| Journal | Europhysics Letters 77, 48003 (2007) |
Abstract
We analyse the size and density of thermally induced regions of close contact in cell:cell contact interfaces within a harmonic potential approximation, estimating these regions to be below one-tenth of a micron across. Our calculations indicate that as the distance between the close contact threshold depth and the mean membrane-membrane separation increases, the density of close contact patches decreases exponentially while there is only a minimal variation in their mean size. The technique developed can be used to calculate the probability of first crossing in reflection symmetry violating systems.
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"abstract": "We analyse the size and density of thermally induced regions of close contact\nin cell:cell contact interfaces within a harmonic potential approximation,\nestimating these regions to be below one-tenth of a micron across. Our\ncalculations indicate that as the distance between the close contact threshold\ndepth and the mean membrane-membrane separation increases, the density of close\ncontact patches decreases exponentially while there is only a minimal variation\nin their mean size. The technique developed can be used to calculate the\nprobability of first crossing in reflection symmetry violating systems.",
"arxiv_id": "physics/0612142",
"authors": [
"Amit K Chattopadhyay",
"Nigel J Burroughs"
],
"categories": [
"physics.bio-ph"
],
"doi": "10.1209/0295-5075/77/48003",
"journal_ref": "Europhysics Letters 77, 48003 (2007)",
"title": "Close contact fluctuations: the seeding of signalling domains in the immunological synapse",
"url": "https://arxiv.org/abs/physics/0612142"
},
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