{
  "annotation_id": "98ab5a83-e24a-48e2-989a-05da29c40f5f",
  "date_created": "2026-03-02T18:01:14.014000Z",
  "date_modified": "2026-03-02T18:01:14.014000Z",
  "file_hash": "4812e06c7e595f47d243e49e7b7e06b409eabdb9abfc61d64694bdc8a50c44fc",
  "private": false,
  "record": {
    "abstract": "We analyse the size and density of thermally induced regions of close contact\nin cell:cell contact interfaces within a harmonic potential approximation,\nestimating these regions to be below one-tenth of a micron across. Our\ncalculations indicate that as the distance between the close contact threshold\ndepth and the mean membrane-membrane separation increases, the density of close\ncontact patches decreases exponentially while there is only a minimal variation\nin their mean size. The technique developed can be used to calculate the\nprobability of first crossing in reflection symmetry violating systems.",
    "arxiv_id": "physics/0612142",
    "authors": [
      "Amit K Chattopadhyay",
      "Nigel J Burroughs"
    ],
    "categories": [
      "physics.bio-ph"
    ],
    "doi": "10.1209/0295-5075/77/48003",
    "journal_ref": "Europhysics Letters 77, 48003 (2007)",
    "title": "Close contact fluctuations: the seeding of signalling domains in the   immunological synapse",
    "url": "https://arxiv.org/abs/physics/0612142"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "99cbb917-808c-4fcf-8ba7-b0f7c1784d6e",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}