{
  "annotation_id": "9683956e-18a3-4918-9471-dc29b1429f5a",
  "date_created": "2026-03-02T18:00:56.091000Z",
  "date_modified": "2026-03-02T18:00:56.091000Z",
  "file_hash": "bb7242e75d9a133f2edd9c2de329ec79837301485e8298ab4cb2f259ce3f9cb5",
  "private": false,
  "record": {
    "abstract": "We study the interaction of lipid bilayers with short chain alcohols using\nmolecular dynamics on different length scales. We use detailed atomistic\nmodeling and modeling on the length scale where an alcohol is just an\namphiphilic dimer. Our strategy is to calibrate a coarse--grained model against\nthe detailed model at selected state points at low alcohol concentration and\nthen perform a wider range of simulations using the coarse--grained model. We\nget semiquantitative agreement with experiment for the major observables such\nas order parameter and area per molecule. We find a linear increase of area per\nmolecule with alcohol concentration. The alcohol molecules in both system\ndescriptions are in close contact with the glycerol backbone. Butanol molecules\ncan enter the bilayer to some extent in contrast to the behavior of shorter\nalcohols. At very high alcohol concentrations we find clearly increased\ninterdigitation between leaflets.",
    "arxiv_id": "physics/0412156",
    "authors": [
      "Allison N. Dickey",
      "Roland Faller"
    ],
    "categories": [
      "physics.bio-ph",
      "physics.comp-ph"
    ],
    "doi": "10.1002/polb.20392",
    "title": "Investigating Interactions of Biomembranes and Alcohols: A Multiscale   Approach",
    "url": "https://arxiv.org/abs/physics/0412156"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "1142ae54-d102-4647-a974-894b51d5efdd",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}