dorsal/arxiv
View SchemaProbing Dynamics at Interfaces: Molecular Motions in Lipid Bilayers studied by Neutron Backscattering
| Authors | Maikel C. Rheinstädter, Tilo Seydel, Tim Salditt |
|---|---|
| Categories | |
| ArXiv ID | physics/0411158 |
| URL | https://arxiv.org/abs/physics/0411158 |
| Journal | Scientific Highlight, ILL Annual Report, p68 (2004). |
Abstract
Lipid membranes in a physiological context cannot be understood without taking into account their mobile environment. Here, we report on a high energy-resolution neutron backscattering study to investigate slow motions on nanosecond time scales in highly oriented solid supported phospholipid bilayers of the model system DMPC -d54 (deuterated 1,2-dimyristoyl-sn-glycero-3-phoshatidylcholine). This technique allows discriminating the Q-dependent onset of mobility and provides a benchmark test regarding the feasibility of dynamical neutron scattering investigations on these sample systems. Apart from freezing of the lipid acyl-chains, we could observe a second freezing temperature that we attribute to the hydration water in between the membrane stacks. The freezing is lowered several degrees as compared to (heavy) bulk water.
{
"annotation_id": "90f65aeb-227c-42dc-81f2-c9896d46ab9e",
"date_created": "2026-03-02T18:00:53.296000Z",
"date_modified": "2026-03-02T18:00:53.296000Z",
"file_hash": "39f6f5089f3337992e0e511b633a9c79b3ae54a6865f891bdb2b115dd25114a1",
"private": false,
"record": {
"abstract": "Lipid membranes in a physiological context cannot be understood without\ntaking into account their mobile environment. Here, we report on a high\nenergy-resolution neutron backscattering study to investigate slow motions on\nnanosecond time scales in highly oriented solid supported phospholipid bilayers\nof the model system DMPC -d54 (deuterated\n1,2-dimyristoyl-sn-glycero-3-phoshatidylcholine). This technique allows\ndiscriminating the Q-dependent onset of mobility and provides a benchmark test\nregarding the feasibility of dynamical neutron scattering investigations on\nthese sample systems. Apart from freezing of the lipid acyl-chains, we could\nobserve a second freezing temperature that we attribute to the hydration water\nin between the membrane stacks. The freezing is lowered several degrees as\ncompared to (heavy) bulk water.",
"arxiv_id": "physics/0411158",
"authors": [
"Maikel C. Rheinst\u00e4dter",
"Tilo Seydel",
"Tim Salditt"
],
"categories": [
"physics.bio-ph"
],
"journal_ref": "Scientific Highlight, ILL Annual Report, p68 (2004).",
"title": "Probing Dynamics at Interfaces: Molecular Motions in Lipid Bilayers studied by Neutron Backscattering",
"url": "https://arxiv.org/abs/physics/0411158"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "b50b4327-e130-464c-8930-79fb91e7ac33",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}