dorsal/arxiv
View SchemaCancer Dissemination: A Consequence of limited Carrying Capacity?
| Authors | Thomas S. Deisboeck, Zhihui Wang |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0610027 |
| URL | https://arxiv.org/abs/q-bio/0610027 |
Abstract
Assuming that there is feedback between an expanding cancer system and its organ-typical microenvironment, we argue here that such local tumor growth is guided by co-existence rather than competition with the surrounding tissue. We then present a novel concept that understands cancer dissemination as a biological mechanism to evade the specific carrying capacity limit of its host organ. This conceptual framework allows us to relate the tumor system's volumetric growth rate to the host organ's functionality-conveying composite infrastructure, and, intriguingly, already provides useful insights into several clinical findings.
{
"annotation_id": "8ff6e327-850b-4c2d-bf2e-2ab64151ba54",
"date_created": "2026-03-02T18:01:34.997000Z",
"date_modified": "2026-03-02T18:01:34.997000Z",
"file_hash": "229c077d610a98ce1701facf185519d7f05e3ecb6aafaec4e378626bae384de3",
"private": false,
"record": {
"abstract": "Assuming that there is feedback between an expanding cancer system and its\norgan-typical microenvironment, we argue here that such local tumor growth is\nguided by co-existence rather than competition with the surrounding tissue. We\nthen present a novel concept that understands cancer dissemination as a\nbiological mechanism to evade the specific carrying capacity limit of its host\norgan. This conceptual framework allows us to relate the tumor system\u0027s\nvolumetric growth rate to the host organ\u0027s functionality-conveying composite\ninfrastructure, and, intriguingly, already provides useful insights into\nseveral clinical findings.",
"arxiv_id": "q-bio/0610027",
"authors": [
"Thomas S. Deisboeck",
"Zhihui Wang"
],
"categories": [
"q-bio.TO"
],
"title": "Cancer Dissemination: A Consequence of limited Carrying Capacity?",
"url": "https://arxiv.org/abs/q-bio/0610027"
},
"schema_id": "dorsal/arxiv",
"source": {
"execution_id": "7bd80936-e247-4a6d-b579-0bcae686e3a6",
"id": "arXiv Dataset IDs",
"type": "Model",
"variant": "snapshot-2026-03-01",
"version": "0.1.0"
},
"user_id": 1000002
}