dorsal/arxiv
View SchemaRecoiling DNA Molecule: Simulation & Experiment
| Authors | Jose Coelho Neto, Ronald Dickman, O. N. Mesquita |
|---|---|
| Categories | |
| ArXiv ID | physics/0203087 |
| URL | https://arxiv.org/abs/physics/0203087 |
| DOI | 10.1016/j.physa.2004.07.029 |
| Journal | Physica A 345, 173-184 (2005) |
Abstract
Single molecule DNA experiments often generate data from force versus extension measurements involving the tethering of a microsphere to one end of a single DNA molecule while the other is attached to a substrate. We show that the persistence length of single DNA molecules can also be measured based on the recoil dynamics of these DNA-microsphere complexes if appropriate corrections are made to the friction coefficient of the microsphere in the vicinity of the substrate. Comparison between computer simulated recoil curves, generated from the corresponding Langevin equation, and experimental recoils is used to assure the validity of data analysis.
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"abstract": "Single molecule DNA experiments often generate data from force versus\nextension measurements involving the tethering of a microsphere to one end of a\nsingle DNA molecule while the other is attached to a substrate. We show that\nthe persistence length of single DNA molecules can also be measured based on\nthe recoil dynamics of these DNA-microsphere complexes if appropriate\ncorrections are made to the friction coefficient of the microsphere in the\nvicinity of the substrate. Comparison between computer simulated recoil curves,\ngenerated from the corresponding Langevin equation, and experimental recoils is\nused to assure the validity of data analysis.",
"arxiv_id": "physics/0203087",
"authors": [
"Jose Coelho Neto",
"Ronald Dickman",
"O. N. Mesquita"
],
"categories": [
"physics.bio-ph",
"cond-mat.stat-mech",
"q-bio"
],
"doi": "10.1016/j.physa.2004.07.029",
"journal_ref": "Physica A 345, 173-184 (2005)",
"title": "Recoiling DNA Molecule: Simulation \u0026 Experiment",
"url": "https://arxiv.org/abs/physics/0203087"
},
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