dorsal/arxiv
View SchemaContinuum model of actin-mediated bacterial propulsion
| Authors | V. G. Benza |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0702061 |
| URL | https://arxiv.org/abs/q-bio/0702061 |
Abstract
The mechanism of propulsion of host bacteria under the action of actin gel networks is examined by means of a continuum model of the dynamics of F-actin concentration. The model includes the elasticity of the network, its attachment to the host and the polymerization at the interface with it. A formula for the cruise velocity is derived wherefrom the contributions of elasticity and polymerization are made explicit. The velocity is proportional to the size of the active portion of the gel, and in turn it elongates its shape. It is shown how a finite latency time is needed for the onset of motion: the related threshold condition is explicitly given. It is numerically found that at steady state the velocity has a pulsating behavior, with sudden decelerations and subsequent recoveries: this unveils the dominant role of the elastic forces in propulsion.
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"abstract": "The mechanism of propulsion of host bacteria under the action of actin gel\nnetworks is examined by means of a continuum model of the dynamics of F-actin\nconcentration. The model includes the elasticity of the network, its attachment\nto the host and the polymerization at the interface with it. A formula for the\ncruise velocity is derived wherefrom the contributions of elasticity and\npolymerization are made explicit.\n The velocity is proportional to the size of the active portion of the gel,\nand in turn it elongates its shape. It is shown how a finite latency time is\nneeded for the onset of motion: the related threshold condition is explicitly\ngiven. It is numerically found that at steady state the velocity has a\npulsating behavior, with sudden decelerations and subsequent recoveries: this\nunveils the dominant role of the elastic forces in propulsion.",
"arxiv_id": "q-bio/0702061",
"authors": [
"V. G. Benza"
],
"categories": [
"q-bio.CB",
"q-bio.BM"
],
"title": "Continuum model of actin-mediated bacterial propulsion",
"url": "https://arxiv.org/abs/q-bio/0702061"
},
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"source": {
"execution_id": "88bbe8f8-600b-4234-8cda-a72d02deda14",
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"type": "Model",
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