dorsal/arxiv
View SchemaSolvable senescence model with positive mutations
| Authors | J. B. Coe, Y. Mao, M. E. Cates |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0411002 |
| URL | https://arxiv.org/abs/q-bio/0411002 |
| DOI | 10.1103/PhysRevE.70.021907 |
| Journal | Physical Review E 70, 021907 (2004) |
Abstract
We build upon our previous analytical results for the Penna model of senescence to include positive mutations. We investigate whether a small but non-zero positive mutation rate gives qualitatively different results to the traditional Penna model in which no positive mutations are considered. We find that the high-lifespan tail of the distribution is radically changed in structure, but that there is not much effect on the bulk of the population. Th e mortality plateau that we found previously for a stochastic generalization of the Penna model is stable to a small positive mutation rate.
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"abstract": "We build upon our previous analytical results for the Penna model of\nsenescence to include positive mutations. We investigate whether a small but\nnon-zero positive mutation rate gives qualitatively different results to the\ntraditional Penna model in which no positive mutations are considered. We find\nthat the high-lifespan tail of the distribution is radically changed in\nstructure, but that there is not much effect on the bulk of the population. Th\ne mortality plateau that we found previously for a stochastic generalization of\nthe Penna model is stable to a small positive mutation rate.",
"arxiv_id": "q-bio/0411002",
"authors": [
"J. B. Coe",
"Y. Mao",
"M. E. Cates"
],
"categories": [
"q-bio.PE"
],
"doi": "10.1103/PhysRevE.70.021907",
"journal_ref": "Physical Review E 70, 021907 (2004)",
"title": "Solvable senescence model with positive mutations",
"url": "https://arxiv.org/abs/q-bio/0411002"
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