dorsal/arxiv
View SchemaAre scale-free regulatory networks larger than random ones?
| Authors | Miguel A. Fortuna, Carlos J. Melian |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0501027 |
| URL | https://arxiv.org/abs/q-bio/0501027 |
Abstract
Network of packages with regulatory interactions (dependences and conflicts) from Debian GNU/Linux operating system is compiled and used as analogy of a gene regulatory network. Using a trace-back algorithm we assembly networks from the potential pool of packages for both scale-free and exponential topology from real and a null model data, respectively. We calculate the maximum number of packages that can be functionally installed in the system (i.e., the active network size). We show that scale-free regulatory networks allow a larger active network size than random ones. Small genomes with scale-free regulatory topology could allow much more functionality than large genomes with an exponential one, with implications on its dynamics, robustness and evolution.
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"abstract": "Network of packages with regulatory interactions (dependences and conflicts)\nfrom Debian GNU/Linux operating system is compiled and used as analogy of a\ngene regulatory network. Using a trace-back algorithm we assembly networks from\nthe potential pool of packages for both scale-free and exponential topology\nfrom real and a null model data, respectively. We calculate the maximum number\nof packages that can be functionally installed in the system (i.e., the active\nnetwork size). We show that scale-free regulatory networks allow a larger\nactive network size than random ones. Small genomes with scale-free regulatory\ntopology could allow much more functionality than large genomes with an\nexponential one, with implications on its dynamics, robustness and evolution.",
"arxiv_id": "q-bio/0501027",
"authors": [
"Miguel A. Fortuna",
"Carlos J. Melian"
],
"categories": [
"q-bio.GN",
"q-bio.MN"
],
"title": "Are scale-free regulatory networks larger than random ones?",
"url": "https://arxiv.org/abs/q-bio/0501027"
},
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"execution_id": "f123f4ff-1b80-421b-ad0b-10d2a14f60c7",
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"type": "Model",
"variant": "snapshot-2026-03-01",
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