dorsal/arxiv
View SchemaOptimal Path to Epigenetic Switching
| Authors | David Marin Roma, Ruadhan A. O'Flanagan, Andrei E. Ruckenstein, Anirvan M. Sengupta, Ranjan Mukhopadhyay |
|---|---|
| Categories | |
| ArXiv ID | q-bio/0406008 |
| URL | https://arxiv.org/abs/q-bio/0406008 |
| DOI | 10.1103/PhysRevE.71.011902 |
Abstract
We use large deviation methods to calculate rates of noise-induced transitions between states in multistable genetic networks. We analyze a synthetic biochemical circuit, the toggle switch, and compare the results to those obtained from a numerical solution of the master equation.
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"abstract": "We use large deviation methods to calculate rates of noise-induced\ntransitions between states in multistable genetic networks. We analyze a\nsynthetic biochemical circuit, the toggle switch, and compare the results to\nthose obtained from a numerical solution of the master equation.",
"arxiv_id": "q-bio/0406008",
"authors": [
"David Marin Roma",
"Ruadhan A. O\u0027Flanagan",
"Andrei E. Ruckenstein",
"Anirvan M. Sengupta",
"Ranjan Mukhopadhyay"
],
"categories": [
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"doi": "10.1103/PhysRevE.71.011902",
"title": "Optimal Path to Epigenetic Switching",
"url": "https://arxiv.org/abs/q-bio/0406008"
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