{
  "annotation_id": "7e0aa6b5-6007-4ca6-b046-07dc052f1603",
  "date_created": "2026-03-02T18:01:31.672000Z",
  "date_modified": "2026-03-02T18:01:31.672000Z",
  "file_hash": "9c6ca49ecbdb4400e1bea1fa5918d638775aaf8312dffebe6460d638911022e8",
  "private": false,
  "record": {
    "abstract": "We use large deviation methods to calculate rates of noise-induced\ntransitions between states in multistable genetic networks. We analyze a\nsynthetic biochemical circuit, the toggle switch, and compare the results to\nthose obtained from a numerical solution of the master equation.",
    "arxiv_id": "q-bio/0406008",
    "authors": [
      "David Marin Roma",
      "Ruadhan A. O\u0027Flanagan",
      "Andrei E. Ruckenstein",
      "Anirvan M. Sengupta",
      "Ranjan Mukhopadhyay"
    ],
    "categories": [
      "q-bio.MN",
      "q-bio.CB"
    ],
    "doi": "10.1103/PhysRevE.71.011902",
    "title": "Optimal Path to Epigenetic Switching",
    "url": "https://arxiv.org/abs/q-bio/0406008"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "db7dbd04-209a-4375-bfdb-d7846a3cbf85",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}