{
  "annotation_id": "7cbcdde8-91d0-4ec8-9876-a50ef9ec8f42",
  "date_created": "2026-03-02T18:01:31.418000Z",
  "date_modified": "2026-03-02T18:01:31.418000Z",
  "file_hash": "c72a240e6f51b2aacf6312bc90fd6e7f502f425a5ade4e4c53cf2b742e04897f",
  "private": false,
  "record": {
    "abstract": "The purpose of research was to check up the influence of decrease of\nnonequality of ventilating (after bronchodilator (berotec) inhalation (BI)) on\nthe magnitude of dynamic compliance of lungs (Cdyn) at asthma patients with\nventilating infringements. Methods and materials: 20 patients (with 2 and 3\ndegrees of ventilating infringements (VC\u003c73%, FEV1\u003c51%, MVV\u003c56%), without\nrestrictive disease of lungs, suffering from bronchial asthma were studied\nbefore and after BI by plotting volume, rate flow, against the transpulmonare\npressure. About the change of nonequality of ventilating we consider by the\nchange after BI of Cdyn, Cdyn at once after flow interruption (Cdyn1), tissue\nresistance at inhalation (Rti in) and exhalation (Rti ex), parameters of\nventilating and general parameters of respiratory mechanics. Results: the\nparameters of ventilating were improved (P \u003c 0,05). General parameters of\nrespiratory mechanics also improved. Rti in and Rti ex are made 0,48+0,16;\n1,05+0,25 kPa/l/s before BI and decreased 0,09+0,04; 0,28+0,09 kPa/l/s after BI\n(P \u003c 0,05; P \u003c 0,05). But Cdyn and Cdyn1 are not changed after BI. Conclusions:\n1. The decrease of ventilation nonequality and tissue friction after BI do not\ninfluence on the initially reduced dynamic compliance of lungs at asthma\npatients without any restrictive diseases of lungs. 2. The cause of not\nincreasing of dynamic compliance after BI probably due by changes in elastic\ncomponent of parenchyma of lungs, insensitive to berotec.",
    "arxiv_id": "q-bio/0402025",
    "authors": [
      "Konstantin F. Tetenev"
    ],
    "categories": [
      "q-bio.TO"
    ],
    "title": "To a Problem of Not Increasing Dynamic Compliance at Asthma Patients   with Ventilating Disorders after Berotec Inhalation",
    "url": "https://arxiv.org/abs/q-bio/0402025"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "7420f0fd-313f-4eec-a33f-19a96e1856d5",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}