dorsal/arxiv
View SchemaChirality Selection in Open Flow Systems and in Polymerization
| Authors | Yukio Saito, Hiroyuki Hyuga |
|---|---|
| Categories | |
| ArXiv ID | physics/0503057 |
| URL | https://arxiv.org/abs/physics/0503057 |
| DOI | 10.1143/JPSJ.74.1629 |
| Journal | J. Phys. Soc. Jpn. 74 (2005) 1629-1635.. |
Abstract
As an attempt to understand the homochirality of organic molecules in life, a chemical reaction model is proposed where the production of chiral monomers from achiral substrate is catalyzed by the polymers of the same enatiomeric type. This system has to be open because in a closed system the enhanced production of chiral monomers by enzymes is compensated by the associated enhancement in back reaction, and the chiral symmetry is conserved. Open flow without cross inhibition is shown to lead to the chirality selection in a general model. In polymerization, the influx of substrate from the ambience and the efflux of chiral products for purposes other than the catalyst production make the system necessarily open. The chiral symmetry is found to be broken if the influx of substrate lies within a finite interval. As the efficiency of the enzyme increases, the maximum value of the enantiomeric excess approaches unity so that the chirality selection becomes complete.
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"abstract": "As an attempt to understand the homochirality of organic molecules in life, a\nchemical reaction model is proposed where the production of chiral monomers\nfrom achiral substrate is catalyzed by the polymers of the same enatiomeric\ntype. This system has to be open because in a closed system the enhanced\nproduction of chiral monomers by enzymes is compensated by the associated\nenhancement in back reaction, and the chiral symmetry is conserved. Open flow\nwithout cross inhibition is shown to lead to the chirality selection in a\ngeneral model. In polymerization, the influx of substrate from the ambience and\nthe efflux of chiral products for purposes other than the catalyst production\nmake the system necessarily open. The chiral symmetry is found to be broken if\nthe influx of substrate lies within a finite interval. As the efficiency of the\nenzyme increases, the maximum value of the enantiomeric excess approaches unity\nso that the chirality selection becomes complete.",
"arxiv_id": "physics/0503057",
"authors": [
"Yukio Saito",
"Hiroyuki Hyuga"
],
"categories": [
"physics.bio-ph",
"physics.chem-ph",
"q-bio.PE"
],
"doi": "10.1143/JPSJ.74.1629",
"journal_ref": "J. Phys. Soc. Jpn. 74 (2005) 1629-1635..",
"title": "Chirality Selection in Open Flow Systems and in Polymerization",
"url": "https://arxiv.org/abs/physics/0503057"
},
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