{
  "annotation_id": "7b7eaf4e-1f3e-4b1b-844d-45d7cad846e6",
  "date_created": "2026-03-02T18:01:11.157000Z",
  "date_modified": "2026-03-02T18:01:11.157000Z",
  "file_hash": "25830e29af9a2281f84753319800e1428eb5afa9b8c9156b7b8ee8a2ef8d15a2",
  "private": false,
  "record": {
    "abstract": "A simulation methodology for predicting the time-course of enzymatic\ndigestions is described. The model is based solely on the enzyme\u0027s subsite\narchitecture and concomitant binding energies. This allows subsite binding\nenergies to be used to predict the evolution of the relative amounts of\ndifferent products during the digestion of arbitrary mixtures of oligomeric or\npolymeric substrates. The methodology has been specifically demonstrated by\nstudying the fragmentation of a population of oligogalacturonides of varying\ndegrees of polymerization, when digested by endo-polygalacturonase II (endo-PG\nII) from Aspergillus niger.",
    "arxiv_id": "physics/0609004",
    "authors": [
      "Jonathan J Hunt",
      "Randall G Cameron",
      "Martin A. K. Williams"
    ],
    "categories": [
      "physics.bio-ph"
    ],
    "title": "On the simulation of enzymatic digest patterns: the fragmentation of   oligomeric and polymeric galacturonides by endo-polygalacturonase II",
    "url": "https://arxiv.org/abs/physics/0609004"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "81fc43f4-def7-485b-a9ef-8964ca1e91d2",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}