{
  "annotation_id": "7a2d81c7-d55c-4722-9bdb-5e9276b4fe03",
  "date_created": "2026-03-02T18:01:10.806000Z",
  "date_modified": "2026-03-02T18:01:10.806000Z",
  "file_hash": "9864c489751c34098ff6b780211801106de39a9f5f22a62d75567fc49811dea3",
  "private": false,
  "record": {
    "abstract": "We present a simple model which allows to investigate equilibrium aspects of\nmolecular recognition between rigid biomolecules on a generic level. Using a\ntwo-stage approach, which consists of a design and a testing step, the role of\ncooperativity and of varying bond strength in molecular recognition is\ninvestigated. Cooperativity is found to enhance selectivity. In complexes which\nrequire a high binding flexibility a small number of strong bonds seems to be\nfavored compared to a situation with many but weak bonds.",
    "arxiv_id": "physics/0608234",
    "authors": [
      "Hans Behringer",
      "Andreas Degenhard",
      "Friederike Schmid"
    ],
    "categories": [
      "physics.bio-ph"
    ],
    "doi": "10.1103/PhysRevLett.97.128101",
    "journal_ref": "Phys. Rev. Lett. 97, 128101 (2006)",
    "title": "A Coarse-Grained Lattice Model for Molecular Recognition",
    "url": "https://arxiv.org/abs/physics/0608234"
  },
  "schema_id": "dorsal/arxiv",
  "source": {
    "execution_id": "46018a03-96bf-42cc-8e88-baf1134a2cfc",
    "id": "arXiv Dataset IDs",
    "type": "Model",
    "variant": "snapshot-2026-03-01",
    "version": "0.1.0"
  },
  "user_id": 1000002
}